| Type | Description |
|---|---|
| Definition | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| Date | Results | Publications |
|---|---|---|
| 2013-11-30 10:47:00 | coordinated interactions between actin (through FlnA) and vesicle trafficking (through Big2-Arf) direct the assembly and disassembly of membrane protein complexes required for neuronal migration and neuroependymal integrity. | 24089482 |
| 2013-06-15 12:06:00 | an early acting GEF (GBF1) activates ARFs that mediate recruitment of late acting GEFs (BIG1/2) to coordinate coating events within the pre-Golgi/Golgi/TGN continuum. | 23386609 |
| 2012-11-17 10:24:00 | Big2 inhibition promotes Filamin A phosphorylation, thereby disrupting cell intrinsic neuronal migration. | 22956851 |
| 2011-03-12 10:21:00 | Results indicate that murine BIG2 is essential for early embryonic development. | 20857375 |
| Type | IDs |
|---|---|
| Synonymous | AI463430, AW493672, BIG2, E230011G24Rik |
| Gene |
UniProtKB-ID:
BIG2_MOUSE
UniprotKB:
A2A5R2
UniParc:
UPI0000192A64
EMBL:
AL591911,
CH466551,
BC158012,
AL591703
Ensembl:
ENSMUSG00000074582
KO:
mmu:99371
|
| Nucleutide sequences |
EMBL-CDS:
AAI58013.1,
EDL06489.1
Ensembl_TRS:
ENSMUST00000099078
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000096677
RefSeq:
XP_006500547.1,
XP_030108138.1,
NP_001078964.1,
XP_036018656.1,
XP_006500546.1
|
| Others |
UniRef100:
UniRef100_A2A5R2
UniRef90:
UniRef90_Q7TSU1
UniRef50:
UniRef50_Q7TSU1
UniGene:
Mm.297192,
Mm.488805
CCDS:
CCDS38335.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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