| Type | Description |
|---|---|
| Definition | DNA cross-link repair 1A |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | The SNM1A DNA repair nuclease. | 32866775 |
| 2019-06-29 10:32:00 | Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink. | 30165656 |
| 2017-07-29 10:50:00 | Strikingly, the addition of the single-stranded DNA (ssDNA)-binding replication protein A (RPA) selectively restores XPF-ERCC1 endonuclease activity on this structure. The 5'-3' exonuclease SNM1A can load from the XPF-ERCC1-RPA-induced incisions and digest past the crosslink to quantitatively complete the unhooking reaction. | 28607004 |
| 2016-06-28 11:32:00 | Different charge distributions along the DNA binding groove may account for the drastic difference in processivity and DNA digestion efficiency, including that of damaged substrates, between SNM1A and SNM1B. | 26582912 |
| 2012-10-13 11:16:00 | differences in the substrate selectivities of SNM1A and SNM1B are likely to be relevant to their in vivo roles | 22692201 |
| Type | IDs |
|---|---|
| Synonymous | PSO2, SNM1, SNM1A |
| Gene |
UniProtKB-ID:
DCR1A_HUMAN
UniprotKB:
Q6PJP8
UniParc:
UPI000006EFFE
EMBL:
D42045,
CH471066,
AY607842,
AL592546,
BC013124,
BC062582
Ensembl:
ENSG00000198924
KO:
hsa:9937
|
| Nucleutide sequences |
EMBL-CDS:
BAA07646.2,
AAH62582.1,
EAW49490.1,
AAT09762.1,
EAW49489.1,
AAH13124.1
Ensembl_TRS:
ENST00000361384,
ENST00000369305
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355185,
ENSP00000358311
RefSeq:
XP_006718153.1,
NP_001258745.1,
NP_055696.3,
XP_011538731.1
|
| Others |
UniRef100:
UniRef100_Q6PJP8
UniRef90:
UniRef90_Q6PJP8
UniRef50:
UniRef50_Q6PJP8
UniGene:
Hs.1560,
Hs.703616
CCDS:
CCDS7584.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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