| Type | Description |
|---|---|
| Definition | Josephin domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1. | 31043700 |
| 2018-02-24 10:26:00 | In this study, the authors report that JOSD1 plays an important role in regulating type-I interferon (IFN-I)-mediated antiviral activity. JOSD1 physically interacts with SOCS1, which is an essential negative regulator of many cytokines signaling, and enhances SOCS1 stability by deubiquitinating K48-linked polyubiquitination of SOCS1. | 28355105 |
| 2010-01-21 00:00:00 | The gain of function studies indicated that Josephin domain containing 1 activate NR5A1 gene expression. | 18579725 |
| Type | IDs |
|---|---|
| Synonymous | dJ508I15.2 |
| Gene |
UniProtKB-ID:
JOS1_HUMAN,
A0A024R1P5_HUMAN
UniprotKB:
Q15040,
A0A024R1P5
UniParc:
UPI000012DABD
EMBL:
CR456473,
CH471095,
AL021707,
AK291827,
BC015026,
D31884
Ensembl:
ENSG00000100221
KO:
hsa:9929
|
| Nucleutide sequences |
EMBL-CDS:
AAH15026.1,
EAW60259.1,
BAA06682.2,
CAG30359.1,
BAF84516.1,
EAW60260.1
Gene_ORFName:
hCG_41699
Ensembl_TRS:
ENST00000216039
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000216039
RefSeq:
NP_001347165.1,
XP_005261935.1,
NP_001347164.1,
NP_055691.1
|
| Others |
UniRef100:
UniRef100_Q15040
UniRef90:
UniRef90_Q15040
UniRef50:
UniRef50_Q15040
UniGene:
Hs.3094
CCDS:
CCDS13976.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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