| Type | Description |
|---|---|
| Definition | IQ motif and Sec7 domain 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:37:00 | An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism. | 33712589 |
| 2021-04-03 13:30:00 | Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex. | 32234213 |
| 2020-04-04 10:44:00 | IQSEC1 variants are the cause of a recessive disease with intellectual disability. | 31607425 |
| 2016-11-05 12:00:00 | both Arf6 activation through GluN2B-BRAG1 during early development and the transition from BRAG1- to BRAG2-dependent Arf6 signaling induced by the GluN2 subunit switch are critical for the development of mature glutamatergic synapses. | 26884337 |
| 2014-09-13 12:01:00 | Brag2 is essential for developmental and pathological angiogenesis by promoting endothelial cell sprouting through regulation of adhesion by beta1-integrin internalization and link for the first time the process of beta1-integrin endocytosis with angiogenesis. | 24522833 |
| Type | IDs |
|---|---|
| Synonymous | ARF-GEP100, ARFGEP100, BRAG2, GEP100 |
| Gene |
UniProtKB-ID:
IQEC1_HUMAN,
B4DGC5_HUMAN,
A0A0C4DGT3_HUMAN
UniprotKB:
Q6DN90,
B4DGC5,
A0A0C4DGT3
UniParc:
UPI00017A6F3D,
UPI000006DF74,
UPI000006E370,
UPI00003E1F36,
UPI00017E10F8
EMBL:
GQ901036,
AC069271,
BC010267,
AK294525,
KF457597,
AB018306,
KF495709,
AY653734,
AC018836,
AC069246
Ensembl:
ENSG00000144711
KO:
hsa:9922
|
| Nucleutide sequences |
EMBL-CDS:
AAH10267.1,
BAA34483.2,
AAT72063.1,
BAG57736.1,
ADO22553.1
Ensembl_TRS:
ENST00000273221,
ENST00000613206,
ENST00000618604
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000273221,
ENSP00000480301,
ENSP00000478001
RefSeq:
NP_001317548.1,
XP_011532615.1,
XP_011532609.1,
NP_055684.3,
XP_011532610.1,
NP_001127854.1,
NP_001363867.1,
XP_011532608.1,
XP_024309614.1,
XP_011532616.1,
XP_024309613.1,
XP_011532613.1,
XP_011532607.1,
XP_011532614.1
|
| Others |
UniRef100:
UniRef100_A0A0C4DGT3,
UniRef100_Q6DN90,
UniRef100_B4DGC5
UniRef90:
UniRef90_A0A2I3M8R3,
UniRef90_Q6DN90,
UniRef90_Q6DN90-3
UniRef50:
UniRef50_A0A2I3M8R3,
UniRef50_Q6DN90
UniGene:
Hs.475506
CCDS:
CCDS74902.1,
CCDS33703.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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