| Type | Description |
|---|---|
| Definition | non-SMC condensin I complex subunit D2 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:25:00 | this is the second report of primary microcephaly due to a pathogenic variant at the NCAPD2 gene. We found two affected siblings who carried a splice-site pathogenic variant (c.3477+2T>C). Our finding provided accurate diagnosis and genetic counseling to the family. | 31056748 |
| 2020-06-06 13:33:00 | NCAPD2 and NCAPD3 expression levels have been confirmed to be significantly up-regulated in the intestinal mucosa of patients with active ulcerative colitis. In vitro, the data suggested that silencing NACPD2 and NACPD3 could depress the expression of IL-1beta, IL-6 and TNF-alpha. Further, knockdown of NACPD2 and NACPD3 could remarkably suppress IKK nucleation and NF-kappaB volume. | 31885422 |
| 2020-04-25 11:51:00 | High NCAPD2 expression was associated with lymph node metastasis in Triple-Negative Breast Cancer. | 31610177 |
| 2016-12-17 10:07:00 | The authors propose that histone H3 threonine 118 phosphorylation via Aurora-A alters the chromatin structure during specific phases of mitosis to promote timely condensin I and cohesin disassociation, which is essential for effective chromosome segregation. | 26878753 |
| 2015-05-16 12:26:00 | Study has shown that both rs7311174 and rs2072374 in the NCAPD2 gene are associated with Parkinson's disease in a Han Chinese population. | 25166511 |
| Type | IDs |
|---|---|
| Synonymous | CAP-D2, CNAP1, MCPH21, hCAP-D2 |
| Gene |
UniProtKB-ID:
CND1_HUMAN,
B3KY03_HUMAN,
B3KMS0_HUMAN
UniprotKB:
Q15021,
B3KY03,
B3KMS0
UniParc:
UPI000015F48D,
UPI00004A2956,
UPI000013C8CA
EMBL:
CH471116,
AC006064,
D63880,
AK128354,
BC028182,
AK022511
Ensembl:
ENSG00000010292
KO:
hsa:9918
|
| Nucleutide sequences |
EMBL-CDS:
EAW88788.1,
BAA09930.2,
EAW88789.1,
AAH28182.1,
BAG54665.1,
BAG51082.1
Ensembl_TRS:
ENST00000315579
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000325017
RefSeq:
NP_055680.3
|
| Others |
UniRef100:
UniRef100_Q15021,
UniRef100_B3KMS0,
UniRef100_B3KY03
UniRef90:
UniRef90_Q15021
UniRef50:
UniRef50_Q15021
UniGene:
Hs.5719
CCDS:
CCDS8548.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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