| Type | Description |
|---|---|
| Definition | adaptor related protein complex 5 subunit zeta 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 10:49:00 | Here, we have generated induced pluripotent stem cells (iPSCs) from patients with two autosomal recessive forms of hereditary spastic paraplegia (HSP) , SPG15 and SPG48, which are caused by mutations in the ZFYVE26 and AP5Z1 genes encoding proteins in the same complex, the spastizin and AP5Z1 proteins, respectively. | 29726929 |
| Type | IDs |
|---|---|
| Synonymous | KIAA0415, SPG48, zeta |
| Gene |
UniProtKB-ID:
AP5Z1_HUMAN
UniprotKB:
O43299
UniParc:
UPI00001C1E75,
UPI00003E5903,
UPI000006F5B4
EMBL:
AB007875,
AC092610,
BC037399,
BC008841
Ensembl:
ENSG00000242802
KO:
hsa:9907
|
| Nucleutide sequences |
EMBL-CDS:
BAA24845.1,
AAH08841.2,
AAH37399.1
Ensembl_TRS:
ENST00000648925,
ENST00000649063
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497815,
ENSP00000496830
RefSeq:
NP_055670.1,
NP_001351787.1
|
| Others |
UniRef100:
UniRef100_O43299
UniRef90:
UniRef90_O43299
UniRef50:
UniRef50_O43299
UniGene:
Hs.558440
CCDS:
CCDS47528.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 29726929 |
Impaired mitochondrial dynamics underlie axonal defects in hereditary spastic paraplegias. Hum Mol Genet Kyle Denton , Yongchao Mou , Chong-Chong Xu , Dhruvi Shah , Jaerak Chang , Craig Blackstone , Xue-Jun Li |
2018-07-15 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25609649 |
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol. Syst. Biol. Xu Li , Wenqi Wang , Jiadong Wang , Anna Malovannaya , Yuanxin Xi , Wei Li , Rudy Guerra , David H Hawke , Jun Qin , Junjie Chen |
2015-01-01 |
ABI1,
ZBTB33,
TCF24,
RPL29P11,
FOXO6,
HDAC6,
HDAC5,
MEF2B,
CHAF1A,
PARP2,
HMGXB4,
SMC4,
FARSB,
HUWE1,
RAD50,
SUGP2,
ABI2,
WASF2,
ALYREF,
TSHZ1,
DDX39A,
TRIB1,
GPHN,
AKAP8,
STAG1,
SF3A1,
TNIP1,
ADAR,
HMG20B,
IRF9,
MYL12B,
MYL9,
CFDP1,
MCRS1,
TOMM40,
CDX2,
COG5,
HOXB13,
LRRC41,
NCOA2,
CEBPB,
KAT5,
SLU7,
DRAP1,
SMC2,
CENPB,
PRPF8,
MXD4,
P3H4,
TRIM3,
ARID3B,
STAG2,
NCKAP1,
IQGAP2,
ZNF268,
UTP14A,
MRPS30,
BRD8,
TCERG1,
MORF4,
POP1,
SF3A3,
SF3B2,
KIF2C,
ATF7,
TMED1,
RCC1,
DDX52,
CHD4,
FOXN3,
PSIP1,
WDHD1,
CHI3L2,
BAZ1A,
NISCH,
CHEK2,
MRPL3,
PNKP,
SGF29,
NACC1,
ACOT7,
LACTB,
DNTTIP1,
FOXP4,
IKBIP,
JDP2,
ANKRD26P1,
HEXIM2,
C17orf49,
NDUFA11,
PUSL1,
COPA,
MAP3K8,
LIN54,
C5orf24,
COX7A2,
CPOX,
CPS1,
NACC2
|
| 22022230 |
The fifth adaptor protein complex. PLoS Biol Jennifer Hirst , Lael D Barlow , Gabriel Casey Francisco , Daniela A Sahlender , Matthew N J Seaman , Joel B Dacks , Margaret S Robinson |
2011-10-01 | - |
| 21903422 |
Immunity Shitao Li , Lingyan Wang , Michael Berman , Young-Yun Kong , Martin E Dorf |
2011-09-23 |
Irf1,
Traf5,
Ubc,
Mib1,
Sarm1,
Azi2,
Txlng,
Unc93b1,
Tbk1,
Ripk3,
Zbp1,
Ripk4,
TANK,
TOM1L1,
FARSB,
ABCB6,
SCAMP3,
OPTN,
CDK3,
CDK4,
CALCOCO2,
IRF9,
CDIPT,
TAB1,
COG5,
CLGN,
CARM1,
HYOU1,
ATG7,
RBCK1,
MORF4L1,
PRDX3,
STIP1,
EBNA1BP2,
YWHAQ,
COPS6,
COPS5,
TLK2,
RIPK3,
CDC37,
GLMN,
IRAK3,
SEC63,
TIRAP,
CHUK,
STK11IP,
CCDC124,
FTSJ3,
CLPTM1,
CREBBP,
MIB2,
CSTF1,
TICAM1,
CTBP1,
CTBP2,
CTNND1,
NFXL1,
DDOST,
DHX9,
TXLNB,
ZNF384,
UBR1,
TXLNA,
STT3B,
EP300,
ACSL3,
FARSA,
FOXK1,
XRN2,
FKBP4,
FKBP5,
DHX30,
TRIM32,
CEP152,
DAAM1,
SNRNP200,
KDM1A,
PEG10,
SARM1,
TAB2,
PDS5A,
UBR2,
FMR1,
NEDD4L,
OBSL1,
DICER1,
TARDBP,
SLC39A14,
PIGN,
GTPBP4,
ZNF346,
DDX58,
ORC3,
EDC4,
TAB3,
YIPF3,
SAMHD1,
LTN1,
RAI14
|
| 20613862 |
PLoS Biol MikoÅaj SÅabicki , Mirko Theis , Dragomir B Krastev , Sergey Samsonov , Emeline Mundwiller , Magno Junqueira , Maciej Paszkowski-Rogacz , Joan Teyra , Anne-Kristin Heninger , Ina Poser , Fabienne Prieur , Jérémy Truchetto , Christian Confavreux , Cécilia Marelli , Alexandra Durr , Jean Philippe Camdessanche , Alexis Brice , Andrej Shevchenko , M Teresa Pisabarro , Giovanni Stevanin , Frank Buchholz |
2010-06-29 | - |
| 18029348 |
Toward a confocal subcellular atlas of the human proteome. Mol Cell Proteomics Laurent Barbe , Emma Lundberg , Per Oksvold , Anna Stenius , Erland Lewin , Erik Björling , Anna Asplund , Fredrik Pontén , Hjalmar Brismar , Mathias Uhlén , Helene Andersson-Svahn |
2008-03-01 | - |
| 16189514 |
Towards a proteome-scale map of the human protein-protein interaction network. Nature Jean-François Rual , Kavitha Venkatesan , Tong Hao , Tomoko Hirozane-Kishikawa , Amélie Dricot , Ning Li , Gabriel F Berriz , Francis D Gibbons , Matija Dreze , Nono Ayivi-Guedehoussou , Niels Klitgord , Christophe Simon , Mike Boxem , Stuart Milstein , Jennifer Rosenberg , Debra S Goldberg , Lan V Zhang , Sharyl L Wong , Giovanni Franklin , Siming Li , Joanna S Albala , Janghoo Lim , Carlene Fraughton , Estelle Llamosas , Sebiha Cevik , Camille Bex , Philippe Lamesch , Robert S Sikorski , Jean Vandenhaute , Huda Y Zoghbi , Alex Smolyar , Stephanie Bosak , Reynaldo Sequerra , Lynn Doucette-Stamm , Michael E Cusick , David E Hill , Frederick P Roth , Marc Vidal |
2005-10-20 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员