例如:"NBL1", "4681", "drought"
收藏
9903 KLHL21

9903

KLHL21

kelch like family member 21

protein-coding

Homo sapiens

基因描述

Type Description
Definition kelch like family member 21

研究结论

Date Results Publications
2018-10-13 10:33:00 KLHL21 plays an essential role in the tumorigenesis and progression of cholangiocarcinoma. 29574153
2017-09-30 13:43:00 Our study suggests that KLHL21 is a potential target for therapeutic intervention. Our findings also provide novel candidate genes on a genome-wide scale, which may have significant impact on the design and execution of effective therapy of HCC patients. 27769251
2017-05-13 13:43:00 data clearly demonstrate that KLHL21 negatively regulates TNFalpha-activated NF-kappaB signaling via targeting IKKbeta, providing new insight into the mechanisms underlying NF-kappaB regulation in cells. 27387502
2010-01-21 12:32:00 KLHL21 localizes to midzone microtubules in anaphase & recruits aurora B & Cul3 to this region; results suggest that different Cul3 adaptors nonredundantly regulate aurora B during mitosis, possibly by ubiquitinating different pools of aurora B 19995937

名称对应

Type IDs
Gene
UniProtKB-ID: KLH21_HUMAN
UniprotKB: Q9UJP4
UniParc: UPI0000070D85, UPI000013E15D
EMBL: AK075305, AK090472, CH471130, BC034039, BC091648, AB007938, AL591866
Ensembl: ENSG00000162413
KO: hsa:9903
Nucleutide sequences
EMBL-CDS: BAC03453.1, BAG52104.1, AAH91648.1, EAW71559.1, AAH34039.3, BAA32314.2
Ensembl_TRS: ENST00000377658, ENST00000377663
Protein sequencees
Ensembl_PRO: ENSP00000366886, ENSP00000366891
RefSeq: NP_055666.2, NP_001311238.1
Others
UniRef100: UniRef100_Q9UJP4
UniRef90: UniRef90_Q9UJP4
UniRef50: UniRef50_Q9UJP4
UniGene: Hs.7764
CCDS: CCDS30575.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员