| Type | Description |
|---|---|
| Definition | SLIT-ROBO Rho GTPase activating protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2015-07-04 11:34:00 | A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. | 25819436 |
| 2015-01-24 13:13:00 | Nuclear-localized srGAP3 interacts with Brg1. This interaction is mediated by the C-terminal of srGAP3 and the ATPase motif of Brg1. | 24561795 |
| 2014-07-26 10:57:00 | deletion of SRGAP3 provides the most convincing explanation for our patient's phenotype, and our observations lend further weight to a causative role of SRGAP3 haploinsufficiency in mental retardation. | 24300292 |
| 2013-11-23 10:11:00 | conclude that srGAP3 has tumor suppressor-like activity in HMECs, likely through its activity as a negative regulator of Rac1 | 23108406 |
| 2010-06-30 22:07:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | ARHGAP14, MEGAP, SRGAP2, WRP |
| Gene |
UniProtKB-ID:
SRGP3_HUMAN
UniprotKB:
O43295
UniParc:
UPI0000074433,
UPI0000376ABC,
UPI0000074099
EMBL:
AF427144,
AF464189,
AB007871
Ensembl:
ENSG00000196220
KO:
hsa:9901
|
| Nucleutide sequences |
EMBL-CDS:
AAN57784.1,
AAN07095.1,
BAA24841.2
Ensembl_TRS:
ENST00000360413,
ENST00000383836
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000353587,
ENSP00000373347
RefSeq:
XP_011532603.1,
XP_011532597.1,
XP_011532605.1,
NP_001028289.1,
NP_055665.1,
XP_016863069.1,
XP_016863068.1,
XP_024309612.1,
XP_011532598.1,
XP_016863064.1,
XP_024309611.1,
XP_016863065.1,
XP_016863063.1,
XP_024309610.1
|
| Others |
UniRef100:
UniRef100_O43295
UniRef90:
UniRef90_O43295
UniRef50:
UniRef50_O43295
UniGene:
Hs.654743
CCDS:
CCDS2572.1,
CCDS33689.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员