| Type | Description |
|---|---|
| Definition | telomere maintenance 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-13 14:22:00 | Taken together, human high-grade gliomas increase TELO2 mRNA expression, and overexpression of TELO2 mRNA expression correlates with shorter survival outcome, supporting that TELO2 is an oncotarget in human gliomas. | 27329594 |
| 2017-05-20 13:22:00 | TELO2 missense variants result in loss of function, perturb TTT complex stability, and cause an autosomal-recessive syndromic form of Intellectual Disability Disorder. | 27132593 |
| 2014-05-31 11:48:00 | IP7, formed by IP6K2, binds CK2 to enhance its phosphorylation of the Tti1/Tel2 complex, thereby stabilizing DNA-PKcs and ATM. This process stimulates p53 phosphorylation at serine 15 to activate the cell death program. | 24657168 |
| 2013-01-12 10:02:00 | The SAM domain of human TEL2 can inhibit the transcriptional activities of ETS1/2 and TEL1. | 22615925 |
| 2011-01-26 10:31:00 | Data show that that knockdown of either Tti1 or Tel2 causes disassembly of mTORC1 and mTORC2. | 20427287 |
| Type | IDs |
|---|---|
| Synonymous | CLK2, TEL2, YHFS |
| Gene |
UniProtKB-ID:
TELO2_HUMAN,
B4DXS2_HUMAN
UniprotKB:
Q9Y4R8,
B4DXS2
UniParc:
UPI000016961D,
UPI00017A8293
EMBL:
AL031705,
AB014583,
AE006467,
AK302103,
CH471112,
AL080126,
AL137394,
BC017188
Ensembl:
ENSG00000100726
KO:
hsa:9894
|
| Nucleutide sequences |
EMBL-CDS:
AAH17188.1,
EAW85647.1,
EAW85650.1,
CAB70722.1,
AAK61284.1,
BAA31658.3,
EAW85649.1,
CAB45724.1,
BAG63484.1
Ensembl_TRS:
ENST00000262319
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262319
RefSeq:
NP_057195.2,
XP_011521077.1,
XP_011521076.1,
XP_011521078.1,
XP_011521079.1,
XP_011521080.1,
XP_011521075.1,
NP_001338775.1
|
| Others |
UniRef100:
UniRef100_Q9Y4R8,
UniRef100_B4DXS2
UniRef90:
UniRef90_Q9Y4R8,
UniRef90_H3BRS3
UniRef50:
UniRef50_Q9Y4R8,
UniRef50_H3BRS3
UniGene:
Hs.271044
CCDS:
CCDS32363.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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