| Type | Description |
|---|---|
| Definition | NUAK family kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:50:00 | miR-622 is a novel potential biomarker of breast carcinoma and impairs motility of breast cancer cells through targeting NUAK1 kinase. | 32418991 |
| 2020-08-22 15:29:00 | Identification of a nuclear localization signal and importin beta members mediating NUAK1 nuclear import inhibited by oxidative stress. | 31090959 |
| 2020-07-11 10:08:00 | the impaired cell migration and invasion by SNHG1 siRNA could be rescued by cotransfection of miR-145-5p in CNE and HNE-1 cells. LncRNA SNHG1 promoted the expression of NUAK1 by down-regulating miR-145-5p and thus promoted the aggressiveness of nasopharyngeal carcinoma cells through AKT signalling pathway and induced epithelial-mesenchymal transition (EMT). | 29575772 |
| 2019-09-14 10:50:00 | This work identifies NUAK1 as a key facilitator of the adaptive antioxidant response that is associated with aggressive disease and worse outcome in human colorectal cancer. Our data suggest that transient NUAK1 inhibition may provide a safe and effective means for treatment of human colorectal cancer via disruption of intrinsic antioxidant defenses | 29500295 |
| 2019-08-03 10:07:00 | The current study demonstrated that ARK5 is a critical factor involved in SKOV3 cell invasion and ARK5 increases invasive potential by promoting EMT and activating the AktmTORMMPs pathway. | 30720082 |
| Type | IDs |
|---|---|
| Synonymous | ARK5 |
| Gene |
UniProtKB-ID:
NUAK1_HUMAN,
A0A024RBL3_HUMAN
UniprotKB:
O60285,
A0A024RBL3
UniParc:
UPI00000403BC,
UPI000052A443
EMBL:
BC152462,
AB011109,
AK289992,
CH471054,
AC011595,
AK027302,
AC010182
Ensembl:
ENSG00000074590
KO:
hsa:9891
|
| Nucleutide sequences |
EMBL-CDS:
AAI52463.1,
BAA25463.2,
BAB55026.1,
BAF82681.1,
EAW97768.1,
EAW97769.1
Gene_ORFName:
hCG_16103
Ensembl_TRS:
ENST00000261402
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261402
RefSeq:
NP_055655.1
|
| Others |
UniRef100:
UniRef100_O60285
UniRef90:
UniRef90_O60285
UniRef50:
UniRef50_O60285
UniGene:
Hs.524692
CCDS:
CCDS31892.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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