| Type | Description |
|---|---|
| Definition | Rho related BTB domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:32:00 | Screening Identifies Novel Roles for RhoBTB1 and RhoBTB3 in Membrane Trafficking Events in Mammalian Cells. | 32354068 |
| 2020-03-21 10:53:00 | RhoBTB1 associates with ROCK1 and ROCK2 and its association with ROCK1 is via its Rho domain. | 31431478 |
| 2018-03-03 11:55:00 | RhoBTB1 regulates the integrity of the Golgi complex through METTL7B. RhoBTB1 is required for expression of METTL7B and silencing of either protein leads to fragmentation of the Golgi. Loss of RhoBTB1 expression is linked to Golgi fragmentation in breast cancer cells. Restoration of normal RhoBTB1 expression rescues Golgi morphology and dramatically inhibits breast cancer cell invasion. | 28219369 |
| 2014-01-11 11:42:00 | we found that miR-31 acts as an oncogene in colon cancer and identified RhoBTB1 as a new target of miR-31 further study demonstrated that miR-31 contributed to the development of colon cancer at least partly by targeting RhoBTB1. | 23258531 |
| 2010-01-21 00:00:00 | Frequent allelic loss and decreased expression of RHOBTB1 suggested that this gene has a role in tumorigenesis of a subset of HNSCC (Head-Neck Squamous Cell Carcinoma). | 16170569 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RHBT1_HUMAN,
A0A024QZL4_HUMAN
UniprotKB:
O94844,
A0A024QZL4
UniParc:
UPI000000D9B7
EMBL:
AK075129,
CH471083,
BC032848,
AB018283,
BC041791
Ensembl:
ENSG00000072422
KO:
hsa:9886
|
| Nucleutide sequences |
EMBL-CDS:
AAH41791.1,
AAH32848.1,
BAC11421.1,
BAA34460.2,
EAW54217.1,
EAW54213.1,
EAW54216.1,
EAW54215.1
Gene_ORFName:
hCG_40241
Ensembl_TRS:
ENST00000337910,
ENST00000357917
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000350595,
ENSP00000338671
RefSeq:
NP_001337836.1,
XP_024304041.1,
NP_001337837.1,
NP_001337835.1,
NP_001337840.1,
NP_001229288.1,
NP_001337832.1,
NP_001337831.1,
XP_016872491.1,
NP_001337839.1,
NP_055651.1,
NP_001337838.1,
NP_001337834.1,
XP_011538727.1,
XP_024304038.1,
XP_011538730.1,
XP_006718148.1,
XP_011538728.1,
XP_024304039.1,
XP_016872489.1,
NP_001337833.1,
XP_011538726.1,
XP_024304040.1
|
| Others |
UniRef100:
UniRef100_O94844
UniRef90:
UniRef90_O94844
UniRef50:
UniRef50_Q9BYZ6
UniGene:
Hs.737374
CCDS:
CCDS7261.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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