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9883 POM121

9883

POM121

POM121 transmembrane nucleoporin

protein-coding

Homo sapiens

基因描述

Type Description
Definition POM121 transmembrane nucleoporin

研究结论

Date Results Publications
2020-11-21 13:34:00 G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. 32673563
2019-05-18 11:50:00 POM121 promotes prostate cancer progression by enhancing importin-dependent nuclear transport of key oncogenic (E2F1, MYC) and prostate cancer-specific (AR-GATA2) transcription factors 30100187
2019-05-18 10:44:00 Taken together, these results showed that full-length Pom121 enables efficient HIV-1 pre-integration complex nuclear import, and suggested that this process may rely on KPNB1 dependent classical cargo nuclear transportation way. 29957337
2017-02-25 12:21:00 findings implicate alternate transcription initiation as a mechanism to increase the functional diversity of NPC components, such as POM121 27198230
2016-07-02 10:21:00 The conserved features of the NLSs of ScHeh1, ScHeh2, and RnPom121 and the effective sorting of Heh2-derived reporters in human cells suggest that active import is conserved but confined to a small subset of INM proteins. 26179916

名称对应

Type IDs
Synonymous P145, POM121A
Gene
UniProtKB-ID: P121A_HUMAN
UniprotKB: Q96HA1
UniParc: UPI000013DA6B, UPI00017BE7A5, UPI0000071A6B
EMBL: BC001518, AB014518, AL713666, AK022555, AK292548, AB289621, BC008794, AC005488, AL080109
Ensembl: ENSG00000196313
KO: hsa:9883
Nucleutide sequences
EMBL-CDS: BAF85237.1, BAF80887.1, BAA31593.2, CAB45713.1, AAH01518.2, CAD28472.1, BAB14097.1, AAH08794.1
Ensembl_TRS: ENST00000434423, ENST00000395270, ENST00000446813, ENST00000627934, ENST00000358357
Protein sequencees
Ensembl_PRO: ENSP00000351124, ENSP00000486504, ENSP00000378687, ENSP00000393020, ENSP00000405562
RefSeq: NP_001374615.1, NP_001374622.1, NP_001374628.1, NP_001374626.1, NP_001374634.1, NP_001244119.1, NP_001374617.1, NP_001374629.1, NP_001374624.1, NP_001374614.1, NP_001374627.1, NP_001374620.1, NP_001374618.1, NP_742017.1, NP_001374625.1, NP_001374621.1, NP_001374630.1, NP_001354539.1, NP_001374631.1, NP_001374633.1, NP_001374616.1, NP_001374632.1, NP_001374623.1
Others
UniRef100: UniRef100_Q96HA1
UniRef90: UniRef90_Q96HA1
UniRef50: UniRef50_Q96HA1
UniGene: Hs.655217, Hs.737064
CCDS: CCDS59059.1, CCDS5542.1

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