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988 CDC5L

988

CDC5L

cell division cycle 5 like

protein-coding

Homo sapiens

基因描述

Type Description
Definition cell division cycle 5 like

研究结论

Date Results Publications
2021-02-27 13:53:00 ANXA7 promotes the cell cycle, proliferation and cell adhesion-mediated drug resistance of multiple myeloma cells by up-regulating CDC5L. 32526706
2019-08-31 10:57:00 One target of CDC5L, ARGN, mediated the strong phenotypic consequences of NEAT1 reduction. 29871935
2017-04-29 11:04:00 Study demonstrates that the levels of Prp19 and Cdc5L are overexpressed in hepatocellular carcinoma (HCC). Prp19 binds with Cdc5L and its downregulation results in reduction of Cdc5L. Mechanistic insights reveal that silencing Prp19 compromises translation activity of Cdc5L and facilitates lysosome-induced degradation of Cdc5L in HCC cells. 28387715
2017-02-18 10:55:00 CDC5L might play an important role in glioma cell survival and disease progression. 26490980
2016-07-02 11:16:00 Cdc5L was highly expressed in hepatocellular carcinoma. Overexpression of Cdc5L favors cell cycle progress of HCC cells, while downregulation of Cdc5L results in cell cycle arrest at G2/M phase and reduced cell proliferation of HCC cells. 26553251

名称对应

Type IDs
Synonymous CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1
Gene
UniProtKB-ID: CDC5L_HUMAN
UniprotKB: Q99459
UniParc: UPI000006EE42
EMBL: BC001568, D85423, AY518540, U86753, AL133262, AB007892, AL353588
Ensembl: ENSG00000096401
KO: hsa:988
Nucleutide sequences
EMBL-CDS: AAH01568.1, BAA24862.2, AAB61210.1, AAR89913.1, BAA20885.1
Ensembl_TRS: ENST00000371477
Protein sequencees
Ensembl_PRO: ENSP00000360532
RefSeq: NP_001244.1
Others
UniRef100: UniRef100_Q99459
UniRef90: UniRef90_Q99459
UniRef50: UniRef50_Q99459
UniGene: Hs.485471
CCDS: CCDS4912.1

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