| Type | Description |
|---|---|
| Definition | SET domain bifurcated histone lysine methyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Knockout of SETDB1 gene using the CRISPR/cas-9 system increases migration and transforming activities via complex regulations of E-cadherin, beta-catenin, and Akt. | 32972752 |
| 2021-03-13 13:18:00 | SETDB1 promotes the progression of colorectal cancer via epigenetically silencing p21 expression. | 32393761 |
| 2021-03-06 13:27:00 | Evidence that miR-152-3p is a positive regulator of SETDB1-mediated H3K9 histone methylation and serves as a toggle between histone and DNA methylation. | 32768498 |
| 2021-02-20 13:33:00 | SETDB1-Mediated Silencing of Retroelements. | 32486217 |
| 2021-01-16 15:54:00 | Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer. | 32473242 |
| Type | IDs |
|---|---|
| Synonymous | ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21 |
| Gene |
UniProtKB-ID:
SETB1_HUMAN
UniprotKB:
Q15047
UniParc:
UPI000002B372,
UPI0000135897,
UPI0000456250
EMBL:
AL590133,
BC028671,
BC009362,
D31891,
CH471121
Ensembl:
ENSG00000143379
KO:
hsa:9869
|
| Nucleutide sequences |
EMBL-CDS:
BAA06689.2,
AAH09362.1,
AAH28671.1,
EAW53506.1
Ensembl_TRS:
ENST00000368962,
ENST00000368969,
ENST00000271640
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357958,
ENSP00000271640,
ENSP00000357965
RefSeq:
NP_036564.3,
NP_001353347.1,
XP_016858444.1,
NP_001353346.1,
NP_001230420.1,
NP_001138887.1
|
| Others |
UniRef100:
UniRef100_Q15047
UniRef90:
UniRef90_Q15047
UniRef50:
UniRef50_Q15047
UniGene:
Hs.643565
CCDS:
CCDS58026.1,
CCDS44217.1,
CCDS972.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员