| Type | Description |
|---|---|
| Definition | centrosomal protein 170 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:48:00 | Ccdc61 controls centrosomal localization of Cep170 and is required for spindle assembly and symmetry. | 30354798 |
| 2020-02-15 10:31:00 | SEPT1 function depends on the Golgi matrix protein GOLGA2 and on centrosomal proteins, including CEP170 and components of gamma-tubulin ring complex, to facilitate the perinuclear concentration of Golgi membranes. | 30709970 |
| 2019-07-13 11:14:00 | Study in mutant mice and human cerebral organoids showed that WDR62 deletion resulted in a reduction in the size of mouse brains and organoids due to the disruption of neural progenitor cells. WDR62 interacts with and promotes CEP170 localization to the basal body of primary cilium, where CEP170 recruits KIF2A to disassemble cilium. | 31197141 |
| 2018-01-27 11:26:00 | Data suggest that CDK5RAP2 and CEP170 both interact with microtubule nucleation-promoting region of AKAP350A; CEP68 interacts with distal C-terminal region of AKAP350A; AKAP350A spans the bridge between centrioles. (CDK5RAP2 = CDK5 regulatory subunit associated protein 2; CEP170 = centrosomal protein 170kDa; AKAP350A = A kinase (PRKA) anchor protein (yotiao) 9; CEP68 = centrosomal protein 68kDa) | 29054927 |
| 2013-06-08 11:28:00 | Data indicate that Cep170 association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle. | 23087211 |
| Type | IDs |
|---|---|
| Synonymous | FAM68A, KAB, KIAA0470 |
| Gene |
UniProtKB-ID:
CE170_HUMAN
UniprotKB:
Q5SW79
UniParc:
UPI0000470238,
UPI000013D925,
UPI0000470237
EMBL:
AB022659,
AL606534,
AB022657,
AB007939,
BC050722,
AB022658,
AC092782
Ensembl:
ENSG00000143702,
ENSG00000276725
KO:
hsa:9859
|
| Nucleutide sequences |
EMBL-CDS:
BAA83379.1,
BAA32315.2,
BAA83378.1,
BAA83380.1,
AAH50722.1
Ensembl_TRS:
ENST00000366542,
ENST00000366543,
ENST00000612450,
ENST00000621831,
ENST00000450306,
ENST00000366544
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355500,
ENSP00000355502,
ENSP00000484359,
ENSP00000355501,
ENSP00000482707,
ENSP00000483344
RefSeq:
XP_011542644.1,
XP_011542642.1,
XP_016858431.1,
XP_016858433.1,
XP_016858432.1,
XP_011542640.1,
XP_016858424.1,
XP_011542636.1,
XP_011542639.1,
XP_016858428.1,
XP_011542646.1,
NP_001035863.1,
XP_016858437.1,
XP_016858438.1,
XP_006711906.1,
XP_016858430.1,
XP_016858423.1,
XP_011542641.1,
NP_055627.2,
XP_016858435.1,
XP_016858436.1,
XP_016858421.1,
XP_016858427.1,
XP_016858434.1,
XP_011542637.1,
XP_011542643.1,
XP_011542645.1,
XP_016858429.1,
XP_016858425.1,
XP_016858422.1,
XP_016858439.1,
XP_016858440.1,
XP_011542638.1,
NP_001035864.1,
XP_016858426.1
|
| Others |
UniRef100:
UniRef100_Q5SW79
UniRef90:
UniRef90_Q5SW79
UniRef50:
UniRef50_Q5SW79
UniGene:
Hs.533635
CCDS:
CCDS44338.1,
CCDS44337.1,
CCDS44339.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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