| Type | Description |
|---|---|
| Definition | RUN and SH3 domain containing 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:39:00 | RUSC2 and EHD1 function in a common pathway to positively regulate the basal traffic of Epidermal growth factor receptor from the Golgi compartment to the cell surface to ensure optimal surface receptor levels for subsequent ligand-mediated activation and cellular responses. | 31932478 |
| 2020-06-13 12:28:00 | analysis of structural basis for effector recognition in Rab35/ACAP2 and Rab35/RUSC2 complexes | 30905672 |
| 2020-03-28 10:26:00 | Circ_RUSC2 upregulates the expression of miR-661 target gene SYK and regulates the function of vascular smooth muscle cells | 31199889 |
| 2019-01-05 12:06:00 | AP-4 deficiency causes missorting of ATG9A in diverse cell types, including patient-derived cells, as well as dysregulation of autophagy. | 30262884 |
| 2017-07-29 12:54:00 | Short-term EGF stimulation if of lung tumor cells can increase the interaction between RUSC2 and GIT2, prolonged stimulation leads to a decrease of their interaction through activating Rab35. | 27238570 |
| Type | IDs |
|---|---|
| Synonymous | Iporin, MRT61 |
| Gene |
UniProtKB-ID:
RUSC2_HUMAN
UniprotKB:
Q8N2Y8
UniParc:
UPI00001C1EB0
EMBL:
BC150262,
BC132766,
CH471071,
AB002373,
BC064843,
BC029647,
BC082245,
BC146654,
AL133476,
BC132770
Ensembl:
ENSG00000198853
KO:
hsa:9853
|
| Nucleutide sequences |
EMBL-CDS:
AAH82245.1,
AAI32771.1,
AAI46655.1,
BAA20830.2,
AAH29647.1,
AAH64843.1,
AAI50263.1,
EAW58377.1,
AAI32767.1
Ensembl_TRS:
ENST00000455600,
ENST00000361226
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000355177,
ENSP00000393922
RefSeq:
NP_001129471.1,
NP_055621.2,
NP_001317669.1
|
| Others |
UniRef100:
UniRef100_Q8N2Y8
UniRef90:
UniRef90_Q8N2Y8
UniRef50:
UniRef50_Q8N2Y8
UniGene:
Hs.493796
CCDS:
CCDS35008.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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