Type | Description |
---|---|
Definition | hephaestin |
Date | Results | Publications |
---|---|---|
2020-09-26 13:03:00 | Zinc induces iron egress from intestinal Caco-2 cells via induction of Hephaestin: A role for PI3K in intestinal iron absorption. | 31973819 |
2019-06-01 11:10:00 | Iron supplementation increased surface expression of the iron-efflux complex, and copper depletion knocked down hephaestin (Heph) activity and decreased ferroportin (Fpn) membrane localization. | 30647129 |
2015-03-28 13:15:00 | This review describes function of hephaestin as ferroxidase is essential for iron binding to apotransferrin in the lamina propria of the intestinal mucosa, a process that is important for further transport of iron to the liver by the portal vein. | 24988611 |
2013-08-31 12:04:00 | Iron efflux from human brain microvasculature endothelial cells ferroportin requires the action of an exocytoplasmic ferroxidase which can be either endogenous hephaestin or extracellular ceruloplasmin. | 23640881 |
2012-08-04 11:43:00 | Heph is active in placenta but may not play a key role in placental iron transport. | 22170436 |
Type | IDs |
---|---|
Synonymous | CPL |
Gene |
UniProtKB-ID:
HEPH_HUMAN,
A0A0C4DG76_HUMAN,
E7ES21_HUMAN
UniprotKB:
Q9BQS7,
A0A0C4DG76,
E7ES21
UniParc:
UPI0001891CBC,
UPI000004D26F,
UPI000004D26E,
UPI000004C643,
UPI0001C06560,
UPI0000443FB4
EMBL:
AF148860,
CH471132,
KF459144,
AL157698,
AB014598,
AY358990,
AJ296162,
KF459146,
AL030998,
BC011561
Ensembl:
ENSG00000089472
KO:
hsa:9843
|
Nucleutide sequences |
EMBL-CDS:
BAA31673.2,
EAX05384.1,
EAX05385.1,
AAH11561.1,
EAX05388.1,
AAQ89349.1,
AAK08131.1,
EAX05386.1,
CAC35365.2,
EAX05387.1
Gene_ORFName:
UNQ2562/PRO6242,
hCG_18329
Ensembl_TRS:
ENST00000336279,
ENST00000343002,
ENST00000519389,
ENST00000441993,
ENST00000419594
|
Protein sequencees |
Ensembl_PRO:
ENSP00000337418,
ENSP00000430620,
ENSP00000343939,
ENSP00000411687,
ENSP00000413211
RefSeq:
NP_055614.1,
NP_001354168.1,
NP_001354165.1,
XP_011529376.1,
XP_011529377.1,
NP_001269070.1,
NP_001354171.1,
NP_001354167.1,
NP_001354161.1,
NP_001354170.1,
NP_001354162.1,
NP_001354163.1,
NP_001354169.1,
NP_001124332.1,
NP_001354172.1,
XP_011529375.1,
XP_016885487.1,
NP_620074.3
|
Others |
UniRef100:
UniRef100_E7ES21,
UniRef100_Q9BQS7,
UniRef100_A0A0C4DG76
UniRef90:
UniRef90_F7H208,
UniRef90_Q9BQS7,
UniRef90_A0A5K1TVT7
UniRef50:
UniRef50_Q9Z0Z4,
UniRef50_Q9BQS7
UniGene:
Hs.31720
CCDS:
CCDS14384.3,
CCDS14385.1
|
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