| Type | Description |
|---|---|
| Definition | zinc finger and BTB domain containing 24 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:17:00 | Loss of ZBTB24 impairs nonhomologous end-joining and class-switch recombination in patients with ICF syndrome. | 32865561 |
| 2020-07-25 10:52:00 | ZBTB24 activates the expression of CDCA7 in T cells.ZBTB24 regulates the apoptosis of T cells via CDCA7/TRAIL-R axis. | 31030944 |
| 2020-03-21 11:52:00 | Identification of ZBTB24 protein domains and motifs for heterochromatin localization and transcriptional activation. Domains and motifs important for the biological function of ZBTB24, which provides a basis for understanding the molecular mechanisms underlying the pathogenesis of ICF syndrome. | 31561277 |
| 2019-10-05 12:56:00 | this study expands the clinical and mutation spectrum of Immunodeficiency, Centromeric Instability, and Facial Anomalies Syndrome by analyzing Saudi hypogammaglobulinemia patients and a novel deletion in the ZBTB24 gene | 30511102 |
| 2019-06-29 11:50:00 | Chromatin immunoprecipitation coupled with loss-of-function approaches in model systems revealed common loci bound by ZBTB24 and DNMT3B, where they function to regulate gene body methylation. Genes coordinately regulated by ZBTB24 and DNMT3B are enriched for molecular mechanisms essential for cellular homeostasis, highlighting the importance of the ZBTB24-DNMT3B interplay in maintaining epigenetic patterns | 30085123 |
| Type | IDs |
|---|---|
| Synonymous | BIF1, ICF2, PATZ2, ZNF450 |
| Gene |
UniProtKB-ID:
ZBT24_HUMAN
UniprotKB:
O43167
UniParc:
UPI000013C924,
UPI0000070814
EMBL:
BC117376,
BC036731,
AL109947,
AB007901,
BC117374
Ensembl:
ENSG00000112365
KO:
hsa:9841
|
| Nucleutide sequences |
EMBL-CDS:
AAH36731.1,
BAA23713.2,
AAI17375.1,
AAI17377.1
Ensembl_TRS:
ENST00000230122
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000230122
RefSeq:
NP_055612.2,
NP_001157785.1
|
| Others |
UniRef100:
UniRef100_O43167
UniRef90:
UniRef90_O43167
UniRef50:
UniRef50_O43167
UniGene:
Hs.409876
CCDS:
CCDS34509.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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