Type | Description |
---|---|
Definition | SH3-domain binding protein 4 |
Date | Results | Publications |
---|---|---|
2012-10-27 11:21:00 | SH3BP4 is a negative regulator of the Rag GTPase complex and amino acid-dependent mTORC1 signaling | 22575674 |
2010-01-21 00:00:00 | TTP Ser(245) is the principal target for the modulation of this protein via the AKT signalling cascade. | 19122209 |
Type | IDs |
---|---|
Synonymous | AI594717, AW227605, BOG25 |
Gene |
UniProtKB-ID:
SH3B4_MOUSE
UniprotKB:
Q921I6
UniParc:
UPI0000024B5A
EMBL:
AK041504,
AK028826,
AK043259,
AK032634,
BC034733,
BC012284
Ensembl:
ENSMUSG00000036206
KO:
mmu:98402
|
Nucleutide sequences |
EMBL-CDS:
AAH34733.1,
BAC31506.1,
BAC26140.1,
AAH12284.1,
BAC30966.1,
BAC27961.1
Ensembl_TRS:
ENSMUST00000066279
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000067581
RefSeq:
XP_030099747.1,
XP_030099750.1,
NP_598577.1
|
Others |
UniRef100:
UniRef100_Q921I6
UniRef90:
UniRef90_Q9P0V3
UniRef50:
UniRef50_Q9P0V3
UniGene:
Mm.170983
CCDS:
CCDS15147.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
30811977 |
Cell Rep Pedro Antas , Laura Novellasdemunt , Anna Kucharska , Isobel Massie , Joana Carvalho , Dahmane Oukrif , Emma Nye , Marco Novelli , Vivian S W Li |
2019-02-26 | - |
24457600 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun Qi Cao , Xiaoju Wang , Meng Zhao , Rendong Yang , Rohit Malik , Yuanyuan Qiao , Anton Poliakov , Anastasia K Yocum , Yong Li , Wei Chen , Xuhong Cao , Xia Jiang , Arun Dahiya , Clair Harris , Felix Y Feng , Sundeep Kalantry , Zhaohui S Qin , Saravana M Dhanasekaran , Arul M Chinnaiyan |
2014-01-01 | - |
23604909 |
Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice. Mamm. Genome Mai Nakahara , Hiroki Tateyama , Masatake Araki , Naomi Nakagata , Ken-ichi Yamamura , Kimi Araki |
2013-06-01 |
Rex2,
Cnot6,
Foxp1,
Mta1,
Pop5,
Bmpr1a,
Dnajc5,
Ctbp2,
Celf1,
Mark2,
Sfxn1,
Gli2,
Klf12,
Kpna2,
Alad,
Nedd4,
Pkig,
Plcb4,
Pvt1,
Rbmxl1,
Rbpms,
Rbpj,
Ralbp1,
Rnf2,
Stmn2,
Camkk2,
Etl4,
Hmgcs1,
Daam1,
Tnrc6b,
Tead1,
Tmem11,
Itpk1,
Arl15,
Hmbox1,
Traf3,
Tsix,
Slc25a51,
Tnrc6a,
Tmem161a,
Usp32,
Abcc4,
Pacsin2,
Zfp407,
G3bp1,
Txnl4a,
Sox2ot,
Mreg,
Snhg3,
Zdhhc18,
Txnrd1,
Carhsp1,
Rev1,
Vapb,
Chst12,
Rpl23,
Cyb5b,
Psmd12,
Rnmt,
Setd8,
Rps13,
1110002J07Rik,
2410006H16Rik,
Qrich1,
Wdfy1,
Ten1,
Mier2,
Mutyh,
Ist1,
Fryl,
Rab10os,
Fblim1,
Tti1,
Nln,
Msi2,
Csrnp3,
Sh3bp4
|
22575674 |
SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling. Mol. Cell Young-Mi Kim , Matthew Stone , Tae Hyun Hwang , Yeon-Gil Kim , Jane R Dunlevy , Timothy J Griffin , Do-Hyung Kim |
2012-06-29 |
Sh3bp4,
RRAGB,
RRAGA,
SH3BP4,
RRAGD,
RRAGC
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
19122209 |
TTP at Ser245 phosphorylation by AKT is required for binding to 14-3-3. J. Biochem. Shigeki Chiba , Mie Tokuhara , Eugene Hayato Morita , Shunnosuke Abe |
2009-03-01 |
Akt1,
Sh3bp4
|
18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
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