| Type | Description |
|---|---|
| Definition | lamin B receptor |
| Date | Results | Publications |
|---|---|---|
| 2019-02-23 13:01:00 | Lbr deficiency could be related to Premature Ageing reflected by enhanced accumulation of protein glycation as a biomarker for ageing. | 29081010 |
| 2017-08-12 10:25:00 | The diffusional mobility of full-length LBR shows significant regional variation along the nuclear envelope, consistent with the existence of discrete LBR microdomains and the occurrence of multiple, asymmetrically-spaced anastomoses along the nuclear envelope-endoplasmic reticulum interface. Native LBR may be "configured" by long-range interactions between adjacent transmembrane domains and parts of the NH2 region. | 28118363 |
| 2016-03-05 11:23:00 | These results show a moderate skin differentiation phenotype, which indicates that upregulation of LBR is not the sole contributor to the Hutchinson-Gilford progeria syndrome phenotype. | 26053873 |
| 2016-01-02 12:06:00 | The N-terminal portion of LBR is probably responsible for the binding to HP1b. | 26364738 |
| 2013-03-30 12:11:00 | Study identified LBR- and lamin-A/C-dependent mechanisms tethering heterochromatin to the nuclear envelope. The two tethers are sequentially used during cellular differentiation and development: first the LBR- and then the lamin-A/C-dependent tether. | 23374351 |
| Type | IDs |
|---|---|
| Synonymous | AI505894, C14SR, ic |
| Gene |
UniProtKB-ID:
LBR_MOUSE
UniprotKB:
Q3U9G9
UniParc:
UPI0000020E45
EMBL:
AK161762,
BC014835,
BC010261,
BC021516,
AK151798,
BC042522,
AK033459,
AK166850,
BC029171,
AK030606,
AK028426,
AK167157,
AY148158
Ensembl:
ENSMUSG00000004880
KO:
mmu:98386
|
| Nucleutide sequences |
EMBL-CDS:
BAE36563.1,
AAN76314.1,
BAC27042.1,
BAE20442.1,
BAE39298.1,
AAH21516.1,
BAE39069.1,
AAN76315.1,
AAH14835.1,
AAH29171.1,
AAH42522.1,
AAH10261.1,
BAE20487.1,
BAE30698.1
Ensembl_TRS:
ENSMUST00000005003
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005003
RefSeq:
XP_006497133.1,
XP_017168530.1,
XP_006497134.1,
NP_598576.2
|
| Others |
UniRef100:
UniRef100_Q3U9G9
UniRef90:
UniRef90_Q3U9G9
UniRef50:
UniRef50_Q14739
UniGene:
Mm.4538
CCDS:
CCDS15584.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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