| Type | Description |
|---|---|
| Definition | maternal embryonic leucine zipper kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:54:00 | MELK Accelerates the Progression of Colorectal Cancer via Activating the FAK/Src Pathway. | 32472210 |
| 2020-10-03 12:56:00 | MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway. | 31915116 |
| 2020-09-19 16:29:00 | MELK is Upregulated in Advanced Clear Cell Renal Cell Carcinoma and Promotes Disease Progression by Phosphorylating PRAS40. | 31813279 |
| 2020-07-04 12:41:00 | MELK is a poor biomarker for non-small-cell lung carcinoma patients | 31599664 |
| 2020-06-13 11:15:00 | We analyzed the expression of MELK and two putative targets, Forkhead Box M1 (FOXM1) and Enhancer of Zeste Homolog 2 (EZH2), in a collection of human iCCA by real-time RT-PCR and immunohistochemistry (IHC). The effects on iCCA growth of both the multi-kinase inhibitor OTSSP167 and specific small-interfering RNA (siRNA) against MELK were investigated in iCCA cell lines. | 31861475 |
| Type | IDs |
|---|---|
| Synonymous | HPK38 |
| Gene |
UniProtKB-ID:
MELK_HUMAN,
B7Z1G6_HUMAN
UniprotKB:
Q14680,
B7Z1G6
UniParc:
UPI000206558C,
UPI0001914A8F,
UPI0000417C10,
UPI0000DE2241,
UPI000004776B,
UPI0000417C11,
UPI000191517A,
UPI000206558B,
UPI0000DE2242
EMBL:
AK301131,
AK293284,
AK293423,
BC014039,
AB183428,
AK293447,
AL442063,
AL354932,
AK300761,
AK302374,
CH471071,
AB183427,
AK300821,
AK299164,
D79997
Ensembl:
ENSG00000165304
KO:
hsa:9833
|
| Nucleutide sequences |
EMBL-CDS:
AAH14039.1,
EAW58304.1,
BAH13343.1,
BAH12961.1,
BAH13687.1,
BAH11508.1,
BAF73616.1,
BAA11492.2,
BAH13354.1,
EAW58303.1,
BAH11482.1,
BAF73615.1,
BAH13416.1,
BAH11502.1
Ensembl_TRS:
ENST00000536860,
ENST00000545008,
ENST00000543751,
ENST00000536329,
ENST00000536987,
ENST00000541717,
ENST00000298048
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000439184,
ENSP00000443550,
ENSP00000298048,
ENSP00000437804,
ENSP00000439792,
ENSP00000441596,
ENSP00000445452
RefSeq:
XP_011516380.1,
NP_001243614.1,
XP_011516386.1,
NP_001243616.1,
XP_011516388.1,
NP_055606.1,
NP_001243622.1,
NP_001243619.1,
XP_011516387.1,
XP_011516381.1,
XP_011516382.1,
NP_001243618.1,
NP_001243617.1,
NP_001243621.1,
NP_001243620.1,
XP_011516384.1,
XP_011516378.1,
XP_011516385.1,
XP_011516379.1,
XP_011516383.1
|
| Others |
UniRef100:
UniRef100_Q14680,
UniRef100_B7Z1G6
UniRef90:
UniRef90_Q14680,
UniRef90_Q14680-6
UniRef50:
UniRef50_Q14680
UniGene:
Hs.184339
CCDS:
CCDS59124.1,
CCDS59126.1,
CCDS59127.1,
CCDS59128.1,
CCDS59125.1,
CCDS59123.1,
CCDS6606.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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