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9828 ARHGEF17

9828

ARHGEF17

Rho guanine nucleotide exchange factor 17

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho guanine nucleotide exchange factor 17

研究结论

Date Results Publications
2019-09-21 12:27:00 results provide compelling evidence that ARHGEF17 is a risk gene for Intracranial aneurysm. 29997225
2017-10-14 10:39:00 data implicate TEM4 as an essential regulator of the actin cytoskeleton that ensures proper membrane protrusion at the leading edge of migrating cells and efficient cellular migration via suppression of actomyosin contractility 23825001
2016-07-30 10:28:00 Interaction of the central domain of ARHGEF17 with Mps1. 26953350
2013-08-31 12:02:00 The rho guanine nucleotide exchange factor 17 is drastically alter the effect of cGMP/cGK involving signaling pathways on RhoA-activated downstream effectors. 23195829
2013-02-23 11:54:00 TEM4 contains a novel actin binding domain and binding to actin is essential for TEM4 subcellular localization and activity. 22911862

名称对应

Type IDs
Synonymous P164RHOGEF, RHOGEF17, TEM4, p164-RhoGEF
Gene
UniProtKB-ID: ARHGH_HUMAN
UniprotKB: Q96PE2
UniParc: UPI000004980B
EMBL: CH471076, AK074500, BC137228, BC050031, AB002335, AF378754
Ensembl: ENSG00000110237
KO: hsa:9828
Nucleutide sequences
EMBL-CDS: AAH50031.1, EAW74891.1, AAL11991.1, AAI37229.1, BAA20795.2
Ensembl_TRS: ENST00000263674
Protein sequencees
Ensembl_PRO: ENSP00000263674
RefSeq: XP_016874113.1, NP_055601.2, XP_016874112.1
Others
UniRef100: UniRef100_Q96PE2
UniRef90: UniRef90_Q96PE2
UniRef50: UniRef50_Q96PE2
UniGene: Hs.533719, Hs.573929
CCDS: CCDS8221.1

全选

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研究热度

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