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9826 ARHGEF11

9826

ARHGEF11

Rho guanine nucleotide exchange factor 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition Rho guanine nucleotide exchange factor 11

研究结论

Date Results Publications
2021-04-13 10:09:00 Galphas directly drives PDZ-RhoGEF signaling to Cdc42. 33023908
2020-02-29 11:40:00 results indicate that ARHGEF1 activity in human lymphocytes is involved in controlling actin cytoskeleton dynamics, restraining PI3K/AKT signaling, and confining B lymphocytes and myelocytes within their dedicated functional environment. 30521495
2019-02-02 11:27:00 PDZ-RhoGEF role in the glioblastoma cell invasion and survival.PDZ-RhoGEF is an effector of TROY signaling. 30219706
2019-01-12 11:54:00 ARHGRF11 inhibited the insulin signaling pathway in placenta and may participate in fetal macrosomia in normal glucose tolerance pregnant women 29486856
2018-10-27 10:56:00 SNPs associated with type 2 diabetes and obesity may also increase the risk of developing gestational diabetes mellitus (GDM) in the Chinese population. Among these SNPs, we report for the first time that rs945508 in ARHGEF11, rs10804591 in PLXND1 and rs10245353 in NFE2L3 were associated with GDM. 28554271

名称对应

Type IDs
Synonymous GTRAP48, PDZ-RHOGEF
Gene
UniProtKB-ID: ARHGB_HUMAN
UniprotKB: O15085
UniParc: UPI00001D62A7, UPI000007027F
EMBL: AL157713, AB002378, CH471121, BC057394, AL356104
Ensembl: ENSG00000132694
KO: hsa:9826
Nucleutide sequences
EMBL-CDS: BAA20834.2, EAW52893.1, EAW52894.1, AAH57394.1
Ensembl_TRS: ENST00000361409, ENST00000368194
Protein sequencees
Ensembl_PRO: ENSP00000357177, ENSP00000354644
RefSeq: XP_011508489.1, NP_001364347.1, XP_006711725.1, XP_016858409.1, XP_006711728.1, XP_016858411.1, NP_055599.1, XP_011508491.1, NP_937879.1, XP_011508488.1, XP_006711723.1, XP_005245686.1, NP_001364348.1, XP_016858413.1, XP_006711722.1, XP_016858412.1, XP_011508487.1, XP_006711724.1, XP_005245690.1
Others
UniRef100: UniRef100_O15085
UniRef90: UniRef90_O15085
UniRef50: UniRef50_O15085
UniGene: Hs.516954
CCDS: CCDS1163.1, CCDS1162.1

全选

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