| Type | Description |
|---|---|
| Definition | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| Date | Results | Publications |
|---|---|---|
| 2019-11-02 11:08:00 | The disproportionate kynurenic acid increase in the fetal brain of Kmo(+/-) animals indicates that the maternal Kmo genotype may play a key role in the pathophysiology of schizophrenia. | 30354938 |
| 2019-08-17 12:39:00 | our study shows Kmonull mice had preserved renal function, reduced renal tubule cell injury and apoptosis, and fewer infiltrating neutrophils compared with Kmowt control mice. | 30760699 |
| 2018-06-09 10:48:00 | Study shows that the development of depression-like behavior in the spared nerve injury model requires brain interleukin-1 signaling and activation of neuronal kynurenine 3-monoxygenase, while pain is independent of this pathway. | 28709913 |
| 2018-06-02 11:08:00 | results demonstrate that the elimination of Kmo in mice is associated with multiple gene and functional alterations that appear to duplicate aspects of the psychopathology of several neuropsychiatric disorders. | 28187857 |
| 2017-12-09 11:26:00 | These results suggest that increased KP metabolites reduced chemokine production, resulting in suppressed mortality upon KMO knockdown in EMCV infection. KP metabolites may thus provide an effective strategy for treating acute viral myocarditis. | 27889626 |
| Type | IDs |
|---|---|
| Synonymous | AI046660 |
| Gene |
UniProtKB-ID:
KMO_MOUSE
UniprotKB:
Q91WN4
UniParc:
UPI00006E2250,
UPI00000293D7
EMBL:
BC014683,
AK129011
Ensembl:
ENSMUSG00000039783
KO:
mmu:98256
|
| Nucleutide sequences |
EMBL-CDS:
AAH14683.1
Ensembl_TRS:
ENSMUST00000040250,
ENSMUST00000097458
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000095067,
ENSMUSP00000038914
RefSeq:
NP_598570.1
|
| Others |
UniRef100:
UniRef100_Q91WN4
UniRef90:
UniRef90_Q91WN4
UniRef50:
UniRef50_O15229
UniGene:
Mm.27217
CCDS:
CCDS15548.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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