| Type | Description |
|---|---|
| Definition | cullin 7 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:58:00 | A novel mutation within intron 17 of the CUL7 gene results in appearance of premature termination codon. | 32278698 |
| 2020-12-12 13:27:00 | Cullin-7 (CUL7) is overexpressed in glioma cells and promotes tumorigenesis via NF-kappaB activation. | 32252802 |
| 2020-06-13 12:44:00 | The mutational spectrum of CUL7, OBSL1, and investigation of genotype-phenotype correlation in 3M syndrome has been reported. | 30980518 |
| 2020-02-29 11:10:00 | REVIEW: Cullin-RING E3 Ubiquitin Ligase 7 in Growth Control and Cancer | 31898234 |
| 2020-01-18 11:18:00 | CUL7 prevents Caspase-8 activation by promoting Caspase-8 modification with non-degradative polyubiquitin chains at K215. CUL7 knockdown sensitized cancer cells to TRAIL-induced apoptosis in vitro and in nude mice. | 30807646 |
| Type | IDs |
|---|---|
| Synonymous | 3M1, CUL-7, KIAA0076, dJ20C7.5 |
| Gene |
UniProtKB-ID:
CUL7_HUMAN
UniprotKB:
Q14999
UniParc:
UPI0001BE8116,
UPI000013D603
EMBL:
BC033647,
AL136304,
AK302668,
AL355385,
D38548
Ensembl:
ENSG00000044090
KO:
hsa:9820
|
| Nucleutide sequences |
EMBL-CDS:
AAH33647.1,
BAG63902.1,
BAA07551.2
Ensembl_TRS:
ENST00000265348,
ENST00000535468
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000438788,
ENSP00000265348
RefSeq:
NP_001361801.1,
XP_016867024.1,
NP_001161842.2,
XP_016867023.1,
NP_001361803.1,
XP_006715348.1,
XP_016867029.1,
XP_016867022.1,
XP_016867025.1,
XP_016867027.1,
XP_011513323.1,
NP_055595.2,
XP_011513321.1,
XP_011513322.1,
XP_005249560.1,
NP_001361802.1
|
| Others |
UniRef100:
UniRef100_Q14999
UniRef90:
UniRef90_Q14999
UniRef50:
UniRef50_Q14999
UniGene:
Hs.520136
CCDS:
CCDS4881.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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