| Type | Description |
|---|---|
| Definition | kelch like ECH associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:15:00 | Label-Free Interactome Analysis Revealed an Essential Role of CUL3-KEAP1 Complex in Mediating the Ubiquitination and Degradation of PHD2. | 31763849 |
| 2021-03-28 19:06:00 | KEAP1-driven co-mutations in lung adenocarcinoma unresponsive to immunotherapy despite high tumor mutational burden. | 32866624 |
| 2021-02-27 13:49:00 | Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas. | 32327612 |
| 2021-02-20 13:35:00 | Molecular Mechanisms Underlying Hepatocellular Carcinoma Induction by Aberrant NRF2 Activation-Mediated Transcription Networks: Interaction of NRF2-KEAP1 Controls the Fate of Hepatocarcinogenesis. | 32751080 |
| 2021-02-13 13:20:00 | Protein kinase CK2 activates Nrf2 via autophagic degradation of Keap1 and activation of AMPK in human cancer cells. | 32317087 |
| Type | IDs |
|---|---|
| Synonymous | INrf2, KLHL19 |
| Gene |
UniProtKB-ID:
KEAP1_HUMAN,
A0A024R7C0_HUMAN
UniprotKB:
Q14145,
A0A024R7C0
UniParc:
UPI000007139C
EMBL:
BC002930,
BC002417,
AF361891,
AF361892,
AC011461,
BC021957,
AF361890,
AF361889,
AF361886,
AK056204,
AF361888,
D50922,
BC015945,
CH471106
Ensembl:
ENSG00000079999
KO:
hsa:9817
|
| Nucleutide sequences |
EMBL-CDS:
AAK43722.1,
AAH15945.1,
AAH21957.2,
AAH02417.1,
AAK51082.1,
BAA09481.3,
AAH02930.1,
BAG51647.1,
EAW84111.1,
EAW84110.1,
EAW84112.1
Gene_ORFName:
hCG_28484
Ensembl_TRS:
ENST00000171111,
ENST00000393623
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000171111,
ENSP00000377245
RefSeq:
XP_005260231.1,
NP_987096.1,
XP_011526754.1,
NP_036421.2,
XP_005260230.1
|
| Others |
UniRef100:
UniRef100_Q14145
UniRef90:
UniRef90_Q14145
UniRef50:
UniRef50_Q14145
UniGene:
Hs.465870
CCDS:
CCDS12239.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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