| Type | Description |
|---|---|
| Definition | GIT ArfGAP 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:06:00 | GIT2 deficiency attenuates inflammation-induced expression of pro-labor mediators in human amnion and myometrial cellsdagger. | 30915469 |
| 2017-09-02 10:45:00 | our work identifies DOCK5 as a key regulator of epithelial invasion and metastasis, and demonstrates that suppression of DOCK5 by GIT2 represents a previously unappreciated mechanism for coordination of Rho and Rac GTPases. | 27669437 |
| 2017-08-05 11:10:00 | we discuss recent findings in key physiological systems that exemplify current understanding of the function of this important regulatory complex. Further, we draw attention to gaps in crucial information that remain to be filled to allow a better understanding of the many roles of the GIT-PIX complex in health and disease | 27182061 |
| 2017-07-29 12:54:00 | Short-term EGF stimulation if of lung tumor cells can increase the interaction between RUSC2 and GIT2, prolonged stimulation leads to a decrease of their interaction through activating Rab35. | 27238570 |
| 2015-05-30 13:52:00 | GIT2 plays an important role in MRE11/ATM/H2AX-mediated DNA damage responses. | 25605334 |
| Type | IDs |
|---|---|
| Synonymous | CAT-2, CAT2, PKL |
| Gene |
UniProtKB-ID:
GIT2_HUMAN,
Q6FI58_HUMAN,
Q68DM7_HUMAN,
F8VXI9_HUMAN,
F8W822_HUMAN
UniprotKB:
Q14161,
Q6FI58,
Q68DM7,
F8VXI9,
F8W822
UniParc:
UPI000002AA7B,
UPI00001DFF85,
UPI000002AA7C,
UPI000002AA7A,
UPI000002AA7D,
UPI000002AA7E,
UPI00020CE45F,
UPI000002AA79,
UPI000002AA77,
UPI00020CE465,
UPI000002AA78,
UPI0000161FB1,
UPI000041A0D7,
UPI000012B4C5
EMBL:
CR749340,
BC014223,
AK222736,
CR533568,
AC084876,
BT007312,
BC001379,
D63482,
AB451428,
AF124491
Ensembl:
ENSG00000139436
KO:
hsa:9815
|
| Nucleutide sequences |
EMBL-CDS:
AAD28047.1,
AAH01379.1,
AAP35976.1,
BAA09769.2,
AAH14223.2,
BAG70242.1,
CAG38599.1,
BAD96456.1,
CAH18193.1
Ensembl_TRS:
ENST00000355312,
ENST00000457474,
ENST00000547815,
ENST00000361006,
ENST00000553118,
ENST00000551209,
ENST00000320063
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354282,
ENSP00000450348,
ENSP00000391813,
ENSP00000347464,
ENSP00000447465,
ENSP00000448832,
ENSP00000323833
RefSeq:
XP_016875747.1,
XP_016875748.1,
XP_006719772.1,
XP_006719771.1,
XP_016875749.1,
NP_001128686.1,
XP_006719770.1,
NP_476510.1,
NP_001317083.1,
NP_001128685.1,
NP_001317082.1,
NP_476511.1,
XP_005254054.1,
NP_055591.2,
XP_006719775.1,
XP_006719776.1,
XP_016875750.1,
NP_631940.2
|
| Others |
UniRef100:
UniRef100_Q14161,
UniRef100_F8W822,
UniRef100_Q6FI58,
UniRef100_Q14161-5,
UniRef100_F8VXI9
UniRef90:
UniRef90_F8W822,
UniRef90_F8VXI9,
UniRef90_Q14161-3,
UniRef90_Q14161,
UniRef90_Q6FI58
UniRef50:
UniRef50_Q6FI58,
UniRef50_A0A4W6CQX3,
UniRef50_Q14161,
UniRef50_Q9JLQ2
UniGene:
Hs.434996
CCDS:
CCDS55884.1,
CCDS44969.1,
CCDS9139.1,
CCDS9138.1,
CCDS44968.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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