| Type | Description |
|---|---|
| Definition | DAP3 binding cell death enhancer 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:32:00 | mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway; the OMA1-DELE1-HRI pathway represents a potential therapeutic target that could enable fine-tuning of the integrated stress response for beneficial outcomes in diseases that involve mitochondrial dysfunction | 32132707 |
| 2020-05-30 11:32:00 | the mitochondrial protease OMA1 and the poorly characterized protein DELE1, together with HRI, constitute the missing pathway that is triggered by mitochondrial stress; these findings could be used to inform future strategies to modulate the cellular response to mitochondrial dysfunction in the context of human disease | 32132706 |
| 2011-04-26 13:39:00 | identifies a novel DAP3-binding protein termed death ligand signal enhancer (DELE); demonstrates the biological significance of DELE for apoptosis signal mediated by death receptors | 20563667 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20877624 |
| Type | IDs |
|---|---|
| Synonymous | DELE, KIAA0141 |
| Gene |
UniProtKB-ID:
DELE1_HUMAN
UniprotKB:
Q14154
UniParc:
UPI0000139350
EMBL:
BC011269,
D50931,
BC010452,
BC011926,
BC007855
Ensembl:
ENSG00000081791
KO:
hsa:9812
|
| Nucleutide sequences |
EMBL-CDS:
AAH11926.1,
AAH07855.1,
AAH10452.1,
AAH11269.1,
BAA09490.2
Ensembl_TRS:
ENST00000194118,
ENST00000432126
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000194118,
ENSP00000396225
RefSeq:
XP_024302042.1,
XP_005268604.1,
XP_011536017.1,
NP_001136075.1,
XP_024302043.1,
XP_005268609.1,
XP_006714875.1,
XP_005268605.1,
NP_055588.3,
XP_011536018.1
|
| Others |
UniRef100:
UniRef100_Q14154
UniRef90:
UniRef90_Q14154
UniRef50:
UniRef50_Q14154
UniGene:
Hs.210532
CCDS:
CCDS4268.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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