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9804 TOMM20

9804

TOMM20

translocase of outer mitochondrial membrane 20

protein-coding

Homo sapiens

基因描述

Type Description
Definition translocase of outer mitochondrial membrane 20

研究结论

Date Results Publications
2021-01-23 13:02:00 Translocase of the outer mitochondrial membrane complex subunit 20 (TOMM20) facilitates cancer aggressiveness and therapeutic resistance in chondrosarcoma. 32920118
2019-07-06 12:00:00 TOM70, but not TOM20, clusters in distinct OMM foci, frequently overlapping with sites in which the endoplasmic reticulum (ER) contacts mitochondria. Functionally, TOM70 depletion specifically impairs inositol trisphosphates (IP3)-linked ER to mitochondria Ca(2+) transfer. This phenomenon is dependent on the capacity of TOM70 to interact with IP3-receptors and favor their functional recruitment close to mitochondria. 29395920
2017-12-30 10:53:00 TOMM20 and MCT1 were highly expressed in diffuse large B-cell lymphoma lymphocytes, indicating an OXPHOS phenotype, whereas non-neoplastic lymphocytes in the control samples did not express these markers. 29248132
2017-12-30 10:53:00 TOMM20, MCT1, and MCT4 expression was significantly different in Hodgkin and Reed Sternberg (HRS) cells. HRS have high expression of TOMM20, while tumor associated macrophages have absent TOMM20 expression. Tumor-infiltrating lymphocytes have low TOMM20 expression. Reactive lymph nodes in contrast to cHL tumors had low TOMM20, MCT1, and MCT4 expression in lymphocytes and macrophages. 29248133
2017-06-24 10:19:00 Gsk3beta and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease 27503909

名称对应

Type IDs
Synonymous MAS20, MOM19, TOM20
Gene
UniProtKB-ID: TOM20_HUMAN, A0A024R3W2_HUMAN
UniprotKB: Q15388, A0A024R3W2
UniParc: UPI0000130CA3
EMBL: AF126958, CH471098, BC071994, CR456718, D13641, AF126959, AL732292, BC000882, AK289810, BC107851, BC066335, AF126961, AF126960, AF126962, BC100286
Ensembl: ENSG00000173726
KO: hsa:9804
Nucleutide sequences
EMBL-CDS: AAH00882.1, AAF13354.1, AAI00287.1, AAH66335.1, EAW70003.1, BAF82499.1, BAA02804.1, AAI07852.1, CAG32999.1, AAH71994.1, EAW70004.1
Gene_ORFName: hCG_1810880
Ensembl_TRS: ENST00000366607
Protein sequencees
Ensembl_PRO: ENSP00000355566
RefSeq: NP_055580.1
Others
UniRef100: UniRef100_Q15388
UniRef90: UniRef90_Q15388
UniRef50: UniRef50_Q15388
UniGene: Hs.533192
CCDS: CCDS1603.1

全选

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