| Type | Description |
|---|---|
| Definition | DEP domain containing MTOR-interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | Helicobacter pylori promote inflammation and host defense through the cagA-dependent activation of mTORC1. | 32722876 |
| 2020-11-28 13:10:00 | DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. | 31685947 |
| 2020-04-18 12:24:00 | DEPTOR is a novel protein that functions in CD4(+) T cells to augment immunoregulation in vitro and in vivo | 29969188 |
| 2019-11-09 11:57:00 | findings demonstrate the roles and mechanisms of DEPTOR in the regulation of the renal physiology and pathology, and demonstrate that the loss of DEPTOR in the proximal tubules protects against cisplatin-induced acute kidney injury. | 29670094 |
| 2019-02-23 10:39:00 | Study revealed a novel function of DEPTOR in osteogenic differentiation by inhibiting MEG3-mediated activation of BMP4 signaling, which suggested that DEPTOR could be a therapeutic target for bone loss diseases and skeletal tissue regeneration. | 29973283 |
| Type | IDs |
|---|---|
| Synonymous | Depdc6 |
| Gene |
UniProtKB-ID:
DPTOR_MOUSE,
B2ZRS7_MOUSE,
B2ZRS3_MOUSE
UniprotKB:
Q570Y9,
B2ZRS7,
B2ZRS3
UniParc:
UPI0000F6E6DD,
UPI00005ABF4E,
UPI00001956B2
EMBL:
EU681960,
AK145208,
EU681961,
AK220300,
AK139888,
EU681964
Ensembl:
ENSMUSG00000022419
KO:
mmu:97998
|
| Nucleutide sequences |
EMBL-CDS:
BAE26298.1,
BAD90225.1,
BAE24172.1,
ACD12871.1,
ACD12868.1,
ACD12867.1
Ensembl_TRS:
ENSMUST00000096433,
ENSMUST00000023056
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023056,
ENSMUSP00000094167
RefSeq:
NP_001033026.1,
NP_663445.2
|
| Others |
UniRef100:
UniRef100_B2ZRS7,
UniRef100_Q570Y9
UniRef90:
UniRef90_Q570Y9
UniRef50:
UniRef50_Q570Y9
UniGene:
Mm.295397,
Mm.393497
CCDS:
CCDS27474.1,
CCDS27475.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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