| Type | Description |
|---|---|
| Definition | transmembrane 9 superfamily member 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-29 11:30:00 | results uncovered a novel role of TM9SF4 proteins in alleviating endoplasmic reticulum stress and protecting chemoresistant breast cancer cells from apoptotic/necrotic cell death | 31249383 |
| 2020-01-11 11:25:00 | Results show that TM9SF4 controls the sorting of TMDs at the ER-Golgi interface. Remarkably, sorting of T-R1 in HCT116 cells was different from that in HEK cells: in HCT116 cells, a substantial fraction of T-R1 was localized to the Golgi complex, and it was relocated to the ER by genetic ablation of TM9SF4. | 30301779 |
| 2019-08-24 12:18:00 | The TM9SF4 functions to facilitate mTOR inactivation, resulting in an enhanced autophagic flux, which serves to protect cells from apoptotic cell death. | 29125601 |
| 2016-04-16 10:12:00 | TM9SF4 is a direct target of HIF-1alpha, down-regulated in leukemic cells by hypoxia and involved in cell adhesion. | 25961573 |
| 2016-01-16 11:57:00 | Our study shows for the first time the important role of TM9SF4 in the aberrant constitutive activation of the V-ATPase, and the development of a malignant phenotype. | 25659576 |
| Type | IDs |
|---|---|
| Synonymous | dJ836N17.2 |
| Gene |
UniProtKB-ID:
TM9S4_HUMAN,
B4DH88_HUMAN,
A0A024QYR3_HUMAN
UniprotKB:
Q92544,
B4DH88,
A0A024QYR3
UniParc:
UPI0000206163,
UPI0000D9C73B
EMBL:
D87444,
AK294980,
BK008759,
BC021107,
AL049539,
CH471077,
BC022850,
AK316293
Ensembl:
ENSG00000101337
KO:
hsa:9777
|
| Nucleutide sequences |
EMBL-CDS:
BAA13385.2,
EAW76391.1,
AAH21107.1,
AAH22850.2,
BAG58049.1,
BAH14664.1,
DAA64541.1
Ensembl_TRS:
ENST00000398022
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000381104
RefSeq:
XP_016883648.1,
XP_016883649.1,
XP_016883646.1,
NP_055557.2,
XP_016883643.1,
XP_016883644.1,
XP_016883645.1,
XP_016883650.1,
XP_016883647.1,
NP_001350660.1
|
| Others |
UniRef100:
UniRef100_Q92544,
UniRef100_B4DH88
UniRef90:
UniRef90_Q92544
UniRef50:
UniRef50_Q92544
UniGene:
Hs.654665
CCDS:
CCDS13196.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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