| Type | Description |
|---|---|
| Definition | BCL2 associated transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:24:00 | Bclaf1 is a direct target of HIF-1 and critically regulates the stability of HIF-1alpha under hypoxia. | 32029898 |
| 2020-05-30 11:18:00 | frequently up-regulated in hepatocellular carcinoma and associated with lower survival rates | 30015413 |
| 2020-03-14 11:57:00 | Study identified Bcl2-associated factor 1 (BCLAF1) as a phosphorylation-dependent SDS22 ligand. | 30661852 |
| 2020-02-08 10:52:00 | promotes cell proliferation, invasion and drug-resistance though targeting lncRNA NEAT1 in hepatocellular carcinoma | 31870774 |
| 2019-05-11 10:53:00 | Bclaf1 levels increase in hypoxia in a HIF-1alpha dependent manner. Therefore, Bclaf1 is a novel positive regulator of HIF-1alpha in the hypoxic microenvironment, providing new incentives for promoting Bcalf1 as a potential therapeutic target for an anti-hepatocellular carcinoma strategy. | 30367150 |
| Type | IDs |
|---|---|
| Synonymous | BTF, bK211L9.1 |
| Gene |
UniProtKB-ID:
BCLF1_HUMAN
UniprotKB:
Q9NYF8
UniParc:
UPI0000367806,
UPI0000367805,
UPI000006FCE7,
UPI0000367807
EMBL:
BC144281,
BC063846,
D79986,
BC047687,
BC132780,
BC056894,
AF249273,
AL121713,
BC047887,
CH471051
Ensembl:
ENSG00000029363
KO:
hsa:9774
|
| Nucleutide sequences |
EMBL-CDS:
AAH56894.1,
AAH63846.1,
EAW47951.1,
AAF64304.1,
AAH47887.1,
AAH47687.1,
AAI44282.1,
AAI32781.1,
BAA11481.2,
EAW47950.1
Ensembl_TRS:
ENST00000527759,
ENST00000353331,
ENST00000531224,
ENST00000530767,
ENST00000392348
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000436501,
ENSP00000229446,
ENSP00000376159,
ENSP00000435210,
ENSP00000434826
RefSeq:
NP_001373628.1,
NP_001373627.1,
NP_001373631.1,
NP_001373623.1,
NP_001373626.1,
NP_001070908.1,
NP_001373625.1,
NP_055554.1,
NP_001373629.1,
NP_001373624.1,
NP_001373633.1,
NP_001070909.1,
NP_001350588.1,
NP_001373622.1,
NP_001373630.1,
NP_001287967.1,
NP_001373632.1
|
| Others |
UniRef100:
UniRef100_Q9NYF8
UniRef90:
UniRef90_Q9NYF8
UniRef50:
UniRef50_Q9NYF8
UniGene:
Hs.486542
CCDS:
CCDS47486.1,
CCDS5177.1,
CCDS47485.1,
CCDS75525.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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