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9770 RASSF2

9770

RASSF2

Ras association domain family member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition Ras association domain family member 2

研究结论

Date Results Publications
2020-10-31 13:15:00 The RUNX1-ETO target gene RASSF2 suppresses t(8;21) AML development and regulates Rac GTPase signaling. 32029705
2020-02-29 11:22:00 suggest that circRASSF2 is a central component linking circRNAs to progression of LSCC via an miR-302b-3p/IGF-1R axis 30992382
2019-10-19 10:45:00 RASSF2 methylation was significantly higher in gastric cancer than in noncancerous tissues; RASSF2 gene methylation was not associated with gender and was not associated with lymph node metastasis. 31453724
2018-04-21 10:09:00 Results showed that in the endometrial adenocarcinoma (OEA group) and ovarian clear cell carcinoma (OCC group) groups, the methylation degrees of the RASSF2A promoter were obviously higher than that of the other two groups. The expression level of RASSF2A mRNA in the OEA and OCC groups was lower than that of the other two groups. 29504361
2018-03-10 12:19:00 we confirmed that the RASSF2-PAR-4 axis was mainly responsible for miR-7 functions in CAFs using bioinformatics methods. Overexpression of miR-7 in CAFs led to down-regulation of RASSF2, which dramatically decreased the secretion of PAR-4 from CAFs and then enhanced the proliferation and migration of the co-cultured cancer cells. 27901488

名称对应

Type IDs
Synonymous CENP-34, RASFADIN
Gene
UniProtKB-ID: RASF2_HUMAN
UniprotKB: P50749
UniParc: UPI000007414C, UPI0000001C0A
EMBL: BC110385, AY154472, AY154471, CH471133, CR627436, BC117118, BC117120, AL133354, AK222650, AY154470, D79990, AK291458
Ensembl: ENSG00000101265
KO: hsa:9770
Nucleutide sequences
EMBL-CDS: AAN59977.1, BAF84147.1, BAD96370.1, AAI10386.1, AAI17119.1, EAX10445.1, AAI17121.1, CAH10522.1, BAA11485.2, AAN59975.1, AAN59976.1
Ensembl_TRS: ENST00000379376, ENST00000379400
Protein sequencees
Ensembl_PRO: ENSP00000368710, ENSP00000368684
RefSeq: XP_016883639.1, NP_055552.1, XP_016883641.1, XP_011527713.1, NP_739580.1, XP_011527712.1, XP_016883640.1, XP_005260952.1, XP_016883638.1, XP_016883642.1, XP_011527714.1
Others
UniRef100: UniRef100_P50749
UniRef90: UniRef90_P50749
UniRef50: UniRef50_P50749
UniGene: Hs.631504
CCDS: CCDS13083.1

全选

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