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9768 PCLAF

9768

PCLAF

PCNA clamp associated factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition PCNA clamp associated factor

研究结论

Date Results Publications
2020-12-26 13:13:00 Dysregulated NF-kappaB signal promotes the hub gene PCLAF expression to facilitate nasopharyngeal carcinoma proliferation and metastasis. 32070873
2019-10-05 11:24:00 IL-6 could induce autophagy by expressing NS5ATP9, while NS5ATP9 upregulated IL-6 levels in turn, which further induced autophagy. 29227529
2019-06-29 12:52:00 our biochemical data show that p15PAF impairs primer synthesis by pol eta-PCNA holoenzyme against both damaged and normal DNA templates. In light of our findings, we discuss the possible mechanistic roles of p15PAF in DNA replication and suppression of DNA lesion bypass. 30102405
2019-05-11 10:46:00 MiR-30a-5p frequently downregulated in prostate cancer inhibits cell proliferation via targeting PCLAF 30669858
2019-04-13 10:38:00 Data demonstrated that NDRG1 is critical for mediating LANA to recruit PCNA onto terminal repeat (TR) of KSHV genome, and facilitates viral DNA replication and episome persistence. Findings suggest that NDRG1 plays an important role in KSHV viral genome replication, and provide new clues for understanding of KSHV persistence. 30811506

名称对应

Type IDs
Synonymous KIAA0101, L5, NS5ATP9, OEATC, OEATC-1, OEATC1, PAF, PAF15, p15(PAF), p15/PAF, p15PAF
Gene
UniProtKB-ID: PAF15_HUMAN
UniprotKB: Q15004
UniParc: UPI00001FE643, UPI000003ABC6
EMBL: JN245895, JN245886, JN245891, AF529370, JN245901, BC016782, JN245913, JN245914, JN245883, JN245893, JN245887, JN245945, JN245940, JN245910, JN245911, JN245898, JN245889, JN245882, JN245896, JN245904, BU170434, BC005832, JN245939, AC087632, JN245899, JN245897, JN245903, JN245916, JN245900, JN245906, JN245942, AY598324, JN245905, JN245937, JN245909, JN245907, D14657, AK290748, CH471082, JN245915, JN245892, JN245890, JN245944, BC007101, JN245908, JN245938, JN245888, JN245902, JN245917, JN245912, JN245941, JN245884, JN245885, JN245894, JN245936, JN245943
Ensembl: ENSG00000166803
KO: hsa:9768
Nucleutide sequences
EMBL-CDS: AEW89562.1, AEW89507.1, AEW89522.1, AEW89564.1, AEW89500.1, AEW89503.1, AEW89563.1, AEW89505.1, AEW89502.1, AEW89491.1, AEW89515.1, AEW89490.1, AEW89497.1, AEW89499.1, AEW89512.1, AEW89513.1, AEW89508.1, BAF83437.1, AEW89523.1, AEW89496.1, AEW89488.1, AEW89560.1, AEW89561.1, AEW89514.1, AAH05832.1, AEW89493.1, AEW89518.1, AEW89517.1, BAA03491.2, AEW89509.1, AEW89565.1, AEW89516.1, AEW89498.1, AAH16782.1, AEW89501.1, AEW89521.1, AEW89568.1, AAH07101.1, AAQ09604.1, AEW89567.1, AEW89520.1, AEW89511.1, AEW89519.1, AEW89506.1, AEW89492.1, AEW89569.1, AEW89495.1, AEW89566.1, EAW77679.1, AAT06735.1, AEW89494.1, AEW89510.1, AEW89504.1, AEW89489.1
Gene_ORFName: L5
Ensembl_TRS: ENST00000300035, ENST00000380258
Protein sequencees
Ensembl_PRO: ENSP00000300035, ENSP00000369608
RefSeq: NP_055551.1, NP_001025160.1
Others
UniRef100: UniRef100_Q15004
UniRef90: UniRef90_Q15004
UniRef50: UniRef50_Q15004
UniGene: Hs.81892
CCDS: CCDS32269.1, CCDS10193.1

全选

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研究热度

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