| Type | Description |
|---|---|
| Definition | jade family PHD finger 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-10 11:41:00 | JADE3 was markedly upregulated in colon cancer tissues and correlated with cancer progression and predicted shorter patient survival. JADE3 interacted with the promoters of LGR5 and activated its transcription, by increasing the occupancy of p300 acetyltransferase and histone acetylation on the promoters. These findings suggest an oncogenic role of JADE3 by regulating cancer stem cell-like traits in the colon cancer. | 29660380 |
| Type | IDs |
|---|---|
| Synonymous | JADE-3, PHF16 |
| Gene |
UniProtKB-ID:
JADE3_HUMAN,
A0A024R1A2_HUMAN
UniprotKB:
Q92613,
A0A024R1A2
UniParc:
UPI0000073DE6
EMBL:
BC114487,
AF127774,
CH471164,
BC113880,
Z83822,
BN000289,
D86969
Ensembl:
ENSG00000102221
KO:
hsa:9767
|
| Nucleutide sequences |
EMBL-CDS:
AAD51905.1,
CAE30502.1,
BAA13205.2,
AAI13881.1,
AAI14488.1,
EAW59278.1,
EAW59277.1
Gene_ORFName:
hCG_15707
Ensembl_TRS:
ENST00000611250,
ENST00000614628
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000479377,
ENSP00000481850
RefSeq:
NP_001070913.1,
NP_055550.1
|
| Others |
UniRef100:
UniRef100_Q92613
UniRef90:
UniRef90_Q92613
UniRef50:
UniRef50_Q92613
UniGene:
Hs.371977
CCDS:
CCDS14271.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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