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9765 ZFYVE16

9765

ZFYVE16

zinc finger FYVE-type containing 16

protein-coding

Homo sapiens

基因描述

Type Description
Definition zinc finger FYVE-type containing 16

研究结论

Date Results Publications
2017-07-15 10:33:00 Two SNPs located near the ZFYVE16 gene on chromosome 5 may have played a role in the early, multicompartment sacrocolpopexy failure. 26944198
2010-03-15 11:36:00 Disruption of proper localization to the endosomes and the Y515 phosphorylation of Endofin enhanced MAPK activation suggesting that Endofin negatively modulates EGFR signaling following receptor endocytosis. 19887107
2010-01-21 00:00:00 Facilitates TGF-beta signaling as a scaffold protein to promote the R-Smad-Smad4 complex formation by bringing Smad4 to the proximity of the receptor complex. 17272273
2010-01-21 00:00:00 The key mode of action of was to reduce the level of Smad2 and Smad3 in complex with Smad4 after TGF-beta1 stimulation. 16775010
2010-01-21 00:00:00 our study is the first to identify and validate Endofin, DCBLD2, and KIAA0582 as part of a complex EGF phosphotyrosine signaling network 17570516

名称对应

Type IDs
Synonymous PPP1R69
Gene
UniProtKB-ID: ZFY16_HUMAN
UniprotKB: Q7Z3T8
UniParc: UPI000013F4A0, UPI0001D147A2
EMBL: BX537424, CR933621, AF434817, AC008771, AL833087, AB002303, BC030808
Ensembl: ENSG00000039319
KO: hsa:9765
Nucleutide sequences
EMBL-CDS: CAD89968.1, AAH30808.1, AAL30772.1, CAD97666.1, CAI45932.1, BAA20764.2
Ensembl_TRS: ENST00000505560, ENST00000338008, ENST00000510158
Protein sequencees
Ensembl_PRO: ENSP00000337159, ENSP00000426848, ENSP00000423663
RefSeq: NP_001098721.2, XP_005248689.1, NP_001336363.2, NP_001271166.2, XP_016865585.1, XP_024302038.1, XP_024302039.1, NP_001271165.2, XP_016865581.1, NP_055548.4, XP_024302040.1, XP_016865580.1, XP_024302041.1
Others
UniRef100: UniRef100_Q7Z3T8
UniRef90: UniRef90_Q7Z3T8
UniRef50: UniRef50_Q7Z3T8
UniGene: Hs.482660, Hs.660410
CCDS: CCDS4050.1

全选

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