| Type | Description |
|---|---|
| Definition | thymocyte selection associated high mobility group box |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancer. | 32111241 |
| 2020-08-01 11:07:00 | The VEGF-A induces the expression of transcription factor TOX in T cells to drive exhaustion-specific transcription program in T cells. | 31704735 |
| 2020-07-04 11:47:00 | High TOX expression is associated with pathogenesis of atherosclerosis. | 31949884 |
| 2019-10-05 11:14:00 | TOX is a critical factor for the normal progression of T cell dysfunction and the maintenance of exhausted T cells during chronic infection, and provide a link between the suppression of effector function intrinsic to CD8 T cells and protection against immunopathology | 31207605 |
| 2019-10-05 11:14:00 | hypothesis that TOX-induced exhaustion program serves to prevent the overstimulation of T cells and activation-induced cell death in settings of chronic antigen stimulation such as cancer | 31207604 |
| Type | IDs |
|---|---|
| Synonymous | TOX1 |
| Gene |
UniProtKB-ID:
TOX_HUMAN
UniprotKB:
O94900
UniParc:
UPI0000070A73
EMBL:
BC016665,
AB018351
Ensembl:
ENSG00000198846
KO:
hsa:9760
|
| Nucleutide sequences |
EMBL-CDS:
AAH16665.1,
BAA34528.2
Ensembl_TRS:
ENST00000361421
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354842
RefSeq:
XP_016869574.1,
NP_055544.1
|
| Others |
UniRef100:
UniRef100_O94900
UniRef90:
UniRef90_O94900
UniRef50:
UniRef50_Q66JW3
UniGene:
Hs.491805,
Hs.634856
CCDS:
CCDS34897.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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