| Type | Description |
|---|---|
| Definition | STE20 like kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:37:00 | SLK-mediated actin cytoskeletal reorganization may facilitate force transmission between the contractile units and the extracellular matrix. | 31913659 |
| 2019-06-29 12:16:00 | The inhibition of SLK by RNA interference significantly suppressed the invasion ability of glioma, and on protein level, knock- down of SLK leaded to an up-regulation of E-cadherin and a down-regulation of Vimentin in glioma cells. | 29534578 |
| 2015-12-05 10:57:00 | SLK interacts with Tpr and alpha-actinin-4 in cells, and these protein-protein interactions may control the subcellular localization and the biological activity of SLK. | 26094769 |
| 2014-08-23 10:53:00 | SLK activated ERMs, together with Galphai, are critical for the correct localization of LGN-NuMA force generator complexes and hence for proper spindle orientation. | 24958772 |
| 2014-05-10 11:19:00 | The fact that SLK (LOSK) phosphorylates only a minor isoform 1A of p150(Glued) suggests that transport and microtubule-organizing functions of dynactin are distinctly divided between the two isoforms | 23985322 |
| Type | IDs |
|---|---|
| Synonymous | LOSK, STK2, bA16H23.1, se20-9 |
| Gene |
UniProtKB-ID:
SLK_HUMAN
UniprotKB:
Q9H2G2
UniParc:
UPI0000070709,
UPI000004B6D3
EMBL:
AB002804,
CH471066,
BC064804,
AL138761,
BC047762,
AF273048,
D86959,
BC111565,
BC047885,
AL360170
Ensembl:
ENSG00000065613
KO:
hsa:9748
|
| Nucleutide sequences |
EMBL-CDS:
AAG34908.1,
EAW49617.1,
AAI11566.1,
AAH64804.1,
EAW49615.1,
BAA19655.1,
BAA13195.2,
AAH47762.1,
EAW49616.1,
AAH47885.1,
EAW49618.1
Ensembl_TRS:
ENST00000369755,
ENST00000335753
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000358770,
ENSP00000336824
RefSeq:
NP_001291672.1,
XP_011538703.1,
NP_055535.2
|
| Others |
UniRef100:
UniRef100_Q9H2G2
UniRef90:
UniRef90_Q9H2G2
UniRef50:
UniRef50_Q9H2G2
UniGene:
Hs.591922
CCDS:
CCDS76334.1,
CCDS7553.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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