| Type | Description |
|---|---|
| Definition | SET domain containing 1A, histone lysine methyltransferase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:42:00 | LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kgamma promoter. | 32366932 |
| 2020-11-21 13:18:00 | SETD1A augments sorafenib primary resistance via activating YAP in hepatocellular carcinoma. | 32918976 |
| 2020-04-25 10:08:00 | Results found that SETD1A is highly regulated in the poor outcome triple negative breast cancer (TNBC) cell line and may epigenetically regulate miR205 in TNBCs. | 31552595 |
| 2020-01-18 11:19:00 | SETD1A, but not RBBP5 or ASH2L, was found to interact with the DNA damage repair protein RAD18. | 31076518 |
| 2019-11-30 12:25:00 | H3K4me3 levels positively correlate with WHO grade malignancy in pediatric EPNs and are associated with progression free survival in patients with posterior fossa group A EPNs (PF-EPN-A). Reduction of H3K4me3 by silencing its methyltransferase SETD1A, in primary cultured EPN cells increased cell response to chemotherapy | 31005631 |
| Type | IDs |
|---|---|
| Synonymous | KMT2F, Set1, Set1A |
| Gene |
UniProtKB-ID:
SET1A_HUMAN
UniprotKB:
O15047
UniParc:
UPI00001C1FA9
EMBL:
AB002337,
BC027450,
BC035795,
AC135048
Ensembl:
ENSG00000099381
KO:
hsa:9739
|
| Nucleutide sequences |
EMBL-CDS:
AAH35795.1,
BAA20797.2,
AAH27450.1
Ensembl_TRS:
ENST00000262519
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262519
RefSeq:
XP_016879398.1,
XP_006721169.1,
XP_005255780.1,
XP_024306267.1,
NP_055527.1
|
| Others |
UniRef100:
UniRef100_O15047
UniRef90:
UniRef90_O15047
UniRef50:
UniRef50_O15047
UniGene:
Hs.297483
CCDS:
CCDS32435.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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