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9737 GPRASP1

9737

GPRASP1

G protein-coupled receptor associated sorting protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein-coupled receptor associated sorting protein 1

研究结论

Date Results Publications
2016-04-23 10:29:00 Study demonstrated that binding of clozapine or olanzapine to the 5-HT7 receptor leads to antagonist-mediated lysosomal degradation by exposing key residues in the C-terminal tail that interact with GASP-1 25706089
2013-08-31 12:00:00 Data suggest that specific serine/threonine residues in DRD2 (dopamine receptor D2) are involved in regulation of DRD2 endocytosis by GRK2 (G-protein coupled receptor kinase 2) and GASP1. 23082996
2012-08-25 11:05:00 GASP1 was identified as a potential new serum and biomarker for brain, pancreatic, lung, and breast cancers, and gliomas. 22483848
2012-07-28 11:30:00 GASP-1 is a key regulator of the trafficking and, by extension, functional expression of GPR55 21718301
2012-06-23 10:49:00 LIR was able to induce gains in 1RM and quadriceps CSA similar to those observed after traditional HI. These responses may be related to the concomitant decrease in MSTN and increase in FLST isoforms, GASP-1, and SMAD-7 mRNA gene expression. 21900845

名称对应

Type IDs
Synonymous GASP, GASP-1, GASP1
Gene
UniProtKB-ID: GASP1_HUMAN
UniprotKB: Q5JY77
UniParc: UPI0000073B80
EMBL: AB007903, AY044233, BC114552, AL035427
Ensembl: ENSG00000198932
KO: hsa:9737
Nucleutide sequences
EMBL-CDS: AAK95578.1, AAI14553.1, BAA23715.3
Ensembl_TRS: ENST00000361600, ENST00000537097, ENST00000444152, ENST00000652542, ENST00000415986
Protein sequencees
Ensembl_PRO: ENSP00000393691, ENSP00000409420, ENSP00000355146, ENSP00000498934, ENSP00000445683
RefSeq: NP_055525.3, NP_001171656.1, NP_001092881.1, NP_001092880.1
Others
UniRef100: UniRef100_Q5JY77
UniRef90: UniRef90_Q5JY77
UniRef50: UniRef50_Q5JY77
UniGene: Hs.729265, Hs.731996
CCDS: CCDS35352.1

全选

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