| Type | Description |
|---|---|
| Definition | DDB1 and CUL4 associated factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:20:00 | VprBP mitigates TGF-beta and Activin signaling by promoting Smurf1-mediated type I receptor degradation. | 31291647 |
| 2020-07-11 12:57:00 | lentiviral accessory protein Vpx exploits DCAF1 to counteract Vpx-mediated SAMHD1 degradation | 31003777 |
| 2019-03-09 11:19:00 | HIV-1 Vpr degrades TET2 by CRL4 E3 ligase to sustain IL-6 expression to enhance viral replication and disease progression. | 29883611 |
| 2018-11-17 12:43:00 | Data suggest that HIV-1 vpr mediates polyubiquitination of HLTF by directly loading it onto C-terminal WD40 domain of DCAF1 in complex the CRL4, an E3 ubiquitin ligase. (vpr = vpr gene product of Human immunodeficiency virus 1; HLTF = human helicase like transcription factor; DCAF1 = human Vpr (HIV-1) binding protein; CRL4 = human E3 ubiquitin ligase CRL4) | 29079575 |
| 2018-03-24 11:21:00 | The study suggests that DCAF1 is involved in hepatitis C virus (HCV) replication through regulation of miR-122, and thus provides new insights into the interaction between HCV and the host cell. | 29327233 |
| Type | IDs |
|---|---|
| Synonymous | RIP, VPRBP |
| Gene |
UniProtKB-ID:
DCAF1_HUMAN
UniprotKB:
Q9Y4B6
UniParc:
UPI00005EE23E,
UPI0000073EC9,
UPI00000716AC
EMBL:
AC092037,
AL080145,
BC110371,
BC022792,
AB018343,
AF061935
Ensembl:
ENSG00000145041
KO:
hsa:9730
|
| Nucleutide sequences |
EMBL-CDS:
AAI10372.1,
BAA34520.2,
CAB45738.1,
AAH22792.1,
AAG27134.1
Ensembl_TRS:
ENST00000423656,
ENST00000504652,
ENST00000335891
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000393183,
ENSP00000421724,
ENSP00000338857
RefSeq:
NP_001374512.1,
NP_001374511.1,
NP_001336099.1,
NP_001336097.1,
NP_001374510.1,
NP_001374509.1,
XP_016863039.1,
XP_005276810.1,
XP_005276812.1,
XP_011532575.1,
XP_016863036.1,
XP_011532577.1,
NP_001336098.1,
NP_001374508.1,
NP_001336100.1,
NP_055518.1,
NP_001374507.1,
XP_016863038.1,
NP_001165375.1
|
| Others |
UniRef100:
UniRef100_Q9Y4B6
UniRef90:
UniRef90_Q9Y4B6
UniRef50:
UniRef50_Q9Y4B6
UniGene:
Hs.716623
CCDS:
CCDS74944.1,
CCDS74943.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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