| Type | Description |
|---|---|
| Definition | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:16:00 | Cardioprotective GLP-1 metabolite prevents ischemic cardiac injury by inhibiting mitochondrial trifunctional protein-alpha. | 31985487 |
| 2017-06-10 12:36:00 | These findings suggested that palmitic acid-induced autophagy supports the survival of IECs. Taken together, these results suggested that HADHA is involved in long-chain fatty acid-induced autophagy in IECs, thus providing new insights into the pathology of IBD and revealing novel therapeutic targets of IBD. | 28153718 |
| 2016-02-13 11:45:00 | nonstructural protein 5 (NS5) interacted with hydroxyacyl-CoA dehydrogenase alpha and beta subunits, two components of the mitochondrial trifunctional protein (MTP) involved in LCFA beta-oxidation | 25816318 |
| 2015-12-19 10:08:00 | alphaTFP may modulate CL molecular species composition in murine heart and liver. In addition, L4-CL might not be an essential requirement for mitochondrial supercomplex assembly. | 26251360 |
| 2010-01-21 00:00:00 | Heterozygosity for beta-oxidation defects predisposes to fatty live disease and insulin resistance in aging mice | 15887119 |
| Type | IDs |
|---|---|
| Synonymous | C77020, Mtpa, TP-alpha |
| Gene |
UniProtKB-ID:
ECHA_MOUSE
UniprotKB:
Q8BMS1
UniParc:
UPI00000EB2D2
EMBL:
BC037009,
BC058569,
AK170683,
AK029017,
AK170478,
BC046978,
BC027156
Ensembl:
ENSMUSG00000025745
KO:
mmu:97212
|
| Nucleutide sequences |
EMBL-CDS:
BAC26245.1,
AAH37009.1,
AAH46978.1,
BAE41822.1,
AAH58569.1,
BAE41956.1,
AAH27156.1
Ensembl_TRS:
ENSMUST00000156859
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000120976
RefSeq:
NP_849209.1
|
| Others |
UniRef100:
UniRef100_Q8BMS1
UniRef90:
UniRef90_Q8BMS1
UniRef50:
UniRef50_P40939
UniGene:
Mm.200497
CCDS:
CCDS19155.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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