| Type | Description |
|---|---|
| Definition | ADAMTS like 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 12:33:00 | Findings postulate that abnormal fibrillin microfibril assembly is the general molecular basis of geleophysic dysplasia, and the specific role of ADAMTSL2 may be to inhibit microfibril assembly, whether it be assembly of FBN2 fibrils in the embryonic period or FBN1 fibrils in tendons during the postnatal period. | 30738849 |
| 2019-06-22 15:09:00 | Upon investigating the interaction between LOX and ADAMTSL2 we found that the absence or inhibition of Lox affected ADAMTSL2 molecular forms and reduced its tissue levels. Thus, ADAMTSL2 stability and inter-molecular complexes may depend on the activity of lysyl oxidases. | 29758265 |
| 2018-10-13 10:28:00 | CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. | 28447857 |
| 2018-03-31 10:39:00 | Two compound heterozygous mutations were confirmed in the ADAMTSL2 gene of the patient with geleophysic dysplasia. | 28917829 |
| 2016-10-29 10:19:00 | A novel mutation in ADAMTSL2 (p. Gly421Ser) gene was identified in individuals with Ehlers-Danlos Syndrome. | 26879370 |
| Type | IDs |
|---|---|
| Synonymous | ADAMTSL-2, GPHYSD1 |
| Gene |
UniProtKB-ID:
ATL2_HUMAN
UniprotKB:
Q86TH1
UniParc:
UPI000018CEA2
EMBL:
BX629352,
AB011177,
BX649571,
BX324209,
BC050544
Ensembl:
ENSG00000197859
KO:
hsa:9719
|
| Nucleutide sequences |
EMBL-CDS:
BAA25531.2,
AAH50544.1
Ensembl_TRS:
ENST00000651351,
ENST00000354484,
ENST00000393060
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000498961,
ENSP00000376780,
ENSP00000346478
RefSeq:
NP_001138792.1,
NP_055509.2,
XP_005272295.1,
XP_011517543.2,
XP_005272296.1,
XP_011517544.1
|
| Others |
UniRef100:
UniRef100_Q86TH1
UniRef90:
UniRef90_Q86TH1
UniRef50:
UniRef50_Q86TH1
UniGene:
Hs.522543
CCDS:
CCDS6976.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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