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9712 USP6NL

9712

USP6NL

USP6 N-terminal like

protein-coding

Homo sapiens

基因描述

Type Description
Definition USP6 N-terminal like

研究结论

Date Results Publications
2019-08-10 10:50:00 Study reports that USP6NL is overexpressed in breast cancer, mainly of the basal-like/integrative cluster 10 subtype. Increased USP6NL levels were accompanied by gene amplification and were associated with worse prognosis in the METABRIC dataset. High levels of USP6NL in breast cancer cells delayed endocytosis and degradation of the EGFR, causing chronic AKT activation. 29691252
2017-12-23 11:59:00 Genome-wide significant (GWS) associations in single-nucleotide polymorphism (SNP)-based tests (P < 5 x 10(-8)) were identified for SNPs in PFDN1/HBEGF, USP6NL/ECHDC3, and BZRAP1-AS1. 28183528
2010-06-30 22:06:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614
2010-01-21 00:00:00 RN-tre phosphorylation is critical for efficient hCdc14A association 17371873
2010-01-21 00:00:00 Rab5 signals to the actin cytoskeleton through RN-tre, a previously identified Rab5-specific GTPase-activating protein; RN-tre interacts with both F-actin and actinin-4, an F-actin bundling protein 15152255

名称对应

Type IDs
Synonymous RNTRE, TRE2NL, USP6NL-IT1
Gene
UniProtKB-ID: US6NL_HUMAN, X6RAB3_HUMAN
UniprotKB: Q92738, X6RAB3
UniParc: UPI000000DA06, UPI0003B92845, UPI0000251ED1
EMBL: AL512631, D13644, BC042943, AK292944, AB449916, CF121539, AL590416, CH471072
Ensembl: ENSG00000148429
KO: hsa:9712
Nucleutide sequences
EMBL-CDS: BAF85633.1, BAA02807.2, BAH16659.1, AAH42943.1, EAW86344.1
Ensembl_TRS: ENST00000277575, ENST00000609104, ENST00000379237
Protein sequencees
Ensembl_PRO: ENSP00000476462, ENSP00000277575, ENSP00000368539
RefSeq: NP_001073960.1, XP_006717605.1, XP_011518064.1, XP_024304031.1, XP_016872461.1, XP_016872462.1, NP_055503.1, XP_011518065.1, XP_016872460.1
Others
UniRef100: UniRef100_Q92738, UniRef100_X6RAB3
UniRef90: UniRef90_Q92738
UniRef50: UniRef50_Q92738
UniGene: Hs.498661
CCDS: CCDS53492.1, CCDS44357.1

全选

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