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9704 DHX34

9704

DHX34

DExH-box helicase 34

protein-coding

Homo sapiens

基因描述

Type Description
Definition DExH-box helicase 34

研究结论

Date Results Publications
2021-03-20 13:33:00 Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM. 33205750
2020-03-21 10:31:00 Missense mutation in DHX34 gene is associated with neurodevelopmental disorder. 31256877
2016-06-28 11:49:00 DHX34 activates nonsense-mediated mRNA decay by functioning as a scaffold for SMG1-mediated UPF1 phosphorylation via complex formation with SMG1 and UPF1. 26841701
2015-06-06 10:24:00 DHX34 promotes mRNP remodeling and triggers the conversion from the SURF complex to the DECID complex resulting in NMD activation. 25220460
2013-11-16 12:27:00 DHX34 and NBAS act in concert with core nonsense-mediated mRNA decay factors to co-regulate a large number of endogenous RNA targets. 23828042

名称对应

Type IDs
Synonymous DDX34, HRH1
Gene
UniProtKB-ID: DHX34_HUMAN
UniprotKB: Q14147
UniParc: UPI0000202759
EMBL: D50924, AC008754, AK297692
Ensembl: ENSG00000134815
KO: hsa:9704
Nucleutide sequences
EMBL-CDS: BAG60050.1, BAA09483.2
Ensembl_TRS: ENST00000328771
Protein sequencees
Ensembl_PRO: ENSP00000331907
RefSeq: XP_005259500.1, NP_055496.2, XP_011525852.1, XP_016883013.1, XP_011525853.1
Others
UniRef100: UniRef100_Q14147
UniRef90: UniRef90_Q14147
UniRef50: UniRef50_Q14147
UniGene: Hs.151706
CCDS: CCDS12700.1

全选

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