TRAM2 - translocation associated membrane protein 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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9697 TRAM2

基因描述

Type	Description
Definition	translocation associated membrane protein 2

研究结论

Date	Results	Publications
2015-08-29 11:35:00	results support a role of DAP12 in stabilizing TREM2-CTF, thereby protecting against excessive pro-inflammatory responses.	25957402
2010-06-30 22:06:00	Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)	20379614
2010-01-21 00:00:00	TRAM2, as a part of the translocon, is required for the biosynthesis of type I collagen by coupling the activity of SERCA2b with the activity of the translocon	14749390
2009-04-01 21:32:00	Observational study of gene-disease association. (HuGE Navigator)	19240061

名称对应

Type	IDs
Gene	UniProtKB-ID: TRAM2_HUMAN, A0A024RD84_HUMAN UniprotKB: Q15035, A0A024RD84 UniParc: UPI00000012BF EMBL: CH471081, KU178488, AK291751, D31762, BC028121, AL049611 Ensembl: ENSG00000065308 KO: hsa:9697
Nucleutide sequences	EMBL-CDS: EAX04373.1, AAH28121.1, BAF84440.1, BAA06540.2, ALQ33946.1, EAX04375.1 Gene_ORFName: hCG_20864 Ensembl_TRS: ENST00000182527
Protein sequencees	Ensembl_PRO: ENSP00000182527 RefSeq: XP_011513307.1, NP_036420.1
Others	UniRef100: UniRef100_Q15035 UniRef90: UniRef90_Q15035 UniRef50: UniRef50_Q15035 UniGene: Hs.520182 CCDS: CCDS34477.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32788342	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane. Mol Cell Proteomics Molly M Hannigan , Alyson M Hoffman , J Will Thompson , Tianli Zheng , Christopher V Nicchitta	2020-11-01	-
29507755	VIRMA mediates preferential m⁶A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov Yanan Yue , Jun Liu , Xiaolong Cui , Jie Cao , Guanzheng Luo , Zezhou Zhang , Tao Cheng , Minsong Gao , Xiao Shu , Honghui Ma , Fengqin Wang , Xinxia Wang , Bin Shen , Yizhen Wang , Xinhua Feng , Chuan He , Jianzhao Liu	2018-01-01	-
28514442	Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper	2017-05-25	-
27499293	Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix. Mol. Cell Qiuyue Chen , Bray Denard , Ching-En Lee , Sungwon Han , James S Ye , Jin Ye	2016-08-18	-
26871637	Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell Xinping Yang , Jasmin Coulombe-Huntington , Shuli Kang , Gloria M Sheynkman , Tong Hao , Aaron Richardson , Song Sun , Fan Yang , Yun A Shen , Ryan R Murray , Kerstin Spirohn , Bridget E Begg , Miquel Duran-Frigola , Andrew MacWilliams , Samuel J Pevzner , Quan Zhong , Shelly A Trigg , Stanley Tam , Lila Ghamsari , Nidhi Sahni , Song Yi , Maria D Rodriguez , Dawit Balcha , Guihong Tan , Michael Costanzo , Brenda Andrews , Charles Boone , Xianghong J Zhou , Kourosh Salehi-Ashtiani , Benoit Charloteaux , Alyce A Chen , Michael A Calderwood , Patrick Aloy , Frederick P Roth , David E Hill , Lilia M Iakoucheva , Yu Xia , Marc Vidal	2016-02-11	USH1C, PQBP1, OPTN, RBM5, CDK5, CDK7, RABEPK, SRRM1, NOD1, CD2BP2, RBM14, HAX1, SLC30A9, STK25, SEMA4F, SLC19A2, CETP, SRSF10, SEPT9, ALDH1L1, RCC1, LDB3, AKAP10, SEC63, PHF21B, HELQ, CKB, ERCC8, CLCN2, ZFYVE27, CLPTM1, TTC8, C15orf40, COL1A2, BBS5, ACMSD, DNAJC19, CPA2, C7orf34, CRH, CRK, RDH12, MIPOL1, ZNF688, SLC25A10, NKX2-5, CTNS, CTSD, UPP2, CYBB, CYP11A1, TSTD2, DAO, REM2, DYX1C1, DCN, DDC, GLIS3, DGUOK, DHCR7, DMD, E2F6, TYMP, EGR2, FLCN, EPHX1, EYA4, ETFA, ETV6, FANCC, FANCG, EFEMP1, MICU2, ZUFSP, FCGR3A, ABCB7, FGA, FGFR1, FH, DOLK, KIAA0907, ARHGEF15, SETX, ARHGAP26, SPG20, FMO3, ETHE1, SLC39A14, CDK20, SMUG1, FXN, FTSJ1, MCM9, GABRA2, GAD1, SUMF2, GALT, UNC50, FBXO8
25957402	DAP12 Stabilizes the C-terminal Fragment of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) and Protects against LPS-induced Pro-inflammatory Response. J Biol Chem Li Zhong , Xiao-Fen Chen , Zhen-Lian Zhang , Zhe Wang , Xin-Zhen Shi , Kai Xu , Yun-Wu Zhang , Huaxi Xu , Guojun Bu	2015-06-19	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21697133	Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. Invest. Ophthalmol. Vis. Sci. Mio Oshikawa , Chihiro Tsutsui , Tomoko Ikegami , Yuki Fuchida , Maki Matsubara , Shigeru Toyama , Ron Usami , Kuniyo Ohtoko , Seishi Kato	2011-08-01	LOC100132249, OTX2-AS1, MIR181A2HG, PRH1-PRR4, LINC01311, LOC100652758, HP11026, RBSG2, LINC01023, HP09025, LINC01563, PANO1, LOC101928120, LINC01363, PIGBOS1, LOC101929185, DISC1FP1, HP09053, ANGPTL7, LINC01053, LOC102723665, HP11014, HP08777, CPLX1, DIAPH2-AS1, SRCAP, CEP250, ADD2, LYPD2, CRABP1, CRABP2, FAM78B, AANAT, DDX1, DMXL1, AGL, DSP, ATOH7, FLNA, MAPK8IP3, PSME4, PDS5A, KPNA6, AIPL1, VAX2, ZNF385A, LTN1, PRPF31, GNB3, GOLGB1, BLOC1S2, RCOR2, LINC00907, RAX, HMX1, DDX51, TLX2, CPLX4, ATXN1L, EYS, OTOP3, DPP10-AS1, ARHGDIG, AMTN, MAB21L1, MAK, MATK, MLLT4, MYH10, NEUROD1, NEUROG1, NRL, NUMA1, OTX2, PAX6, IMPG2, PDE6A, CABP2, NBAS, SERPINF1, KIF1A, FAM208B, PRH1, C14orf132, ANO2, RALGAPB, JPH3, KIDINS220, DISP3, PTPRF, RBP3, RCVRN, RXRG, LOC645967, ISL2, SLC1A7, BRCA1, TULP1, CAD
20379614	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Mol. Med. Jed E Rose , FrÃ©dÃ©rique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl	2010-03-17	-
19240061	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. Gut G Trynka , A Zhernakova , J Romanos , L Franke , K A Hunt , G Turner , M Bruinenberg , G A Heap , M Platteel , A W Ryan , C de Kovel , G K T Holmes , P D Howdle , J R F Walters , D S Sanders , C J J Mulder , M L Mearin , W H M Verbeek , V Trimble , F M Stevens , D Kelleher , D Barisani , M T Bardella , R McManus , D A van Heel , C Wijmenga	2009-08-01	-

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