| Type | Description |
|---|---|
| Definition | ciliary rootlet coiled-coil, rootletin |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:26:00 | Up-regulated microRNA-33b inhibits epithelial-mesenchymal transition in gallbladder cancer through down-regulating CROCC. | 31799620 |
| 2021-01-02 12:50:00 | Identification of a Structurally Dynamic Domain for Oligomer Formation in Rootletin. | 32325071 |
| 2019-03-30 11:18:00 | Rootletin forms large, diffusionally stable bifurcating fibers, which amass slowly on mature centrioles over many hours from anaphase. Nascent centrioles (procentrioles), in contrast, do not form roots and must be licensed to do so through PLK1 activity. | 29649211 |
| 2018-11-03 10:21:00 | CEP68 is important in forming rootletin filaments that branch off centrioles and to modulate the thickness of rootletin fibers. | 29463719 |
| 2017-10-07 10:32:00 | It has been proposed that the archetypal linker protein Rootletin maintains centrosome cohesion in part through inhibition of VHL-mediated Cep68 degradation. | 28089774 |
| Type | IDs |
|---|---|
| Synonymous | ROLT, TAX1BP2 |
| Gene |
UniProtKB-ID:
CROCC_HUMAN
UniprotKB:
Q5TZA2
UniParc:
UPI00001AE5A0,
UPI0000073D47
EMBL:
BK005505,
DQ139275,
AB007914,
BX284668,
AF527734,
AL049569
Ensembl:
ENSG00000058453
KO:
hsa:9696
|
| Nucleutide sequences |
EMBL-CDS:
BAA32290.2,
DAA05505.1,
AAP85633.1,
CAI20363.1,
ABA43896.1,
CAH70055.1
Ensembl_TRS:
ENST00000375541
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000364691
RefSeq:
XP_011540770.2,
XP_016858402.2,
XP_024306860.1,
XP_016858404.2,
NP_055490.4,
XP_016858403.2,
XP_024306858.1,
XP_006711121.1,
XP_011540772.2
|
| Others |
UniRef100:
UniRef100_Q5TZA2
UniRef90:
UniRef90_Q5TZA2
UniRef50:
UniRef50_Q5TZA2
UniGene:
Hs.309403
CCDS:
CCDS30616.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员