| Type | Description |
|---|---|
| Definition | proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:53:00 | Wnt/beta-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone. | 31771658 |
| 2020-03-14 11:30:00 | PRG4 plays a role in the maturation of the subchondral bone | 31119776 |
| 2020-03-14 11:22:00 | Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis. | 30070147 |
| 2019-12-14 12:17:00 | Prg4 is present in macrophages in atherosclerotic lesions and critically influences macrophage function, but deletion of Prg4 in bone marrow-derived cells does not affect atherosclerotic lesion development. | 29772480 |
| 2019-11-23 10:37:00 | Prg4 deficiency increases atherosclerosis susceptibility in apolipoprotein E knockout and low-density lipoprotein receptor knockout mice | 30477757 |
| Type | IDs |
|---|---|
| Synonymous | CACP, DOL54, JCAP, MSF, SZP, lubricin |
| Gene |
UniProtKB-ID:
PRG4_MOUSE,
A0A0R4J207_MOUSE,
E0CZ58_MOUSE
UniprotKB:
Q9JM99,
A0A0R4J207,
E0CZ58
UniParc:
UPI00001E2EC8,
UPI00005EE275,
UPI00005EE277,
UPI00005AC8A7,
UPI00005EE276,
UPI00005EE274,
UPI00005EE273
EMBL:
AC161432,
AK149469,
AB034730,
AK132597
Ensembl:
ENSMUSG00000006014
KO:
mmu:96875
|
| Nucleutide sequences |
EMBL-CDS:
BAE21253.1,
BAA92310.1,
BAE28900.1
Ensembl_TRS:
ENSMUST00000162367,
ENSMUST00000006171,
ENSMUST00000164600,
ENSMUST00000161611
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125551,
ENSMUSP00000006171,
ENSMUSP00000125677,
ENSMUSP00000128943
RefSeq:
XP_036010442.1,
XP_036010433.1,
XP_036010441.1,
XP_036010440.1,
XP_036010436.1,
XP_036010418.1,
NP_001103616.1,
NP_067375.3,
XP_036010431.1,
XP_036010446.1,
XP_036010443.1,
XP_036010427.1,
XP_036010444.1,
XP_036010448.1,
XP_036010439.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J207,
UniRef100_Q9JM99,
UniRef100_E0CZ58
UniRef90:
UniRef90_Q9JM99,
UniRef90_Q9JM99-5
UniRef50:
UniRef50_Q9JM99,
UniRef50_Q9JM99-5
UniGene:
Mm.174256,
Mm.329131
CCDS:
CCDS48391.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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