| Type | Description |
|---|---|
| Definition | NEDD4 binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | Integration of innate immune signalling by caspase-8 cleavage of N4BP1. | 32971525 |
| 2020-01-25 11:51:00 | NEDD4-binding protein 1 (N4BP1) is a interferon-inducible inhibitor of HIV-1 in primary T cells and macrophages. N4BP1 harbours a prototypical PilT N terminus-like RNase domain and inhibits HIV-1 replication by interacting with and degrading viral mRNA species. Following activation of CD4(+) T cells, MALT lymphoma associated translocation protein cleaves N4BP1 and facilitates the reactivation of latent HIV-1 proviruses. | 31133753 |
| 2014-08-09 11:05:00 | The p34 interacts with the WW1 domain of NEDD4-1, an interaction that enhances NEDD4-1 stability. | 24141722 |
| 2009-03-25 21:36:00 | Observational study of gene-disease association. (HuGE Navigator) | 19074885 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
N4BP1_HUMAN
UniprotKB:
O75113
UniParc:
UPI000013D2A2
EMBL:
BC108288,
AB014515,
AC023813,
AC026470,
BC152472
Ensembl:
ENSG00000102921
KO:
hsa:9683
|
| Nucleutide sequences |
EMBL-CDS:
AAI08289.1,
AAI52473.1,
BAA31590.2
Ensembl_TRS:
ENST00000262384
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262384
RefSeq:
XP_011521784.1,
NP_694574.3
|
| Others |
UniRef100:
UniRef100_O75113
UniRef90:
UniRef90_O75113
UniRef50:
UniRef50_O75113
UniGene:
Hs.511839
CCDS:
CCDS45479.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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