| Type | Description |
|---|---|
| Definition | DEP domain containing 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:22:00 | Sleep-related hypermotor epilepsy (SHE): Contribution of known genes in 103 patients. | 31835056 |
| 2020-08-22 15:30:00 | A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-beta1 dependent mechanisms. | 30723271 |
| 2020-07-11 12:08:00 | There was a significant correlation between DEPDC5 rs1012068A/C and HBV-related hepatocellular carcinoma in the Han Chinese population. A to C mutation increased the risk of the developing of HBV-related hepatocellular carcinoma. | 30683632 |
| 2020-05-09 10:23:00 | findings of recurrent genomic alterations, together with functional data, validate the DEPDC5 as a bona fide tumor suppressor contributing to GIST progression and a biologically relevant target of the frequent chromosome 22q deletions | 31636198 |
| 2020-03-14 11:29:00 | our data provide the first evidence of behavioral alterations in mice with Depdc5 loss and support mTOR inhibition as a rational therapeutic strategy for DEPDC5-related epilepsy in humans. | 31174205 |
| Type | IDs |
|---|---|
| Synonymous | DEP.5, FFEVF, FFEVF1 |
| Gene |
UniProtKB-ID:
DEPD5_HUMAN
UniprotKB:
O75140
UniParc:
UPI00004708D5,
UPI00004708D4,
UPI000047F6F0,
UPI00017A6DF0,
UPI0000139B73,
UPI000192C426,
UPI00005627F9,
UPI00001CE047
EMBL:
AB014545,
BC136612,
Z82190,
AJ698951,
AK294987,
AL022331,
AJ704764,
Z83856,
AC005004,
CH471095,
CR749304,
AJ698950,
BC146766,
BC057797,
BX640828
Ensembl:
ENSG00000100150
KO:
hsa:9681
|
| Nucleutide sequences |
EMBL-CDS:
CAG27890.1,
AAI36613.1,
CAH18159.1,
BAG58054.1,
CAE45904.1,
CAG28924.1,
EAW59996.1,
CAG27889.1,
AAH57797.1,
BAA31620.2,
AAI46767.1
Ensembl_TRS:
ENST00000400248,
ENST00000400249,
ENST00000400242,
ENST00000645711,
ENST00000382111,
ENST00000642696,
ENST00000644331,
ENST00000535622,
ENST00000651528,
ENST00000382112,
ENST00000646755
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383107,
ENSP00000371545,
ENSP00000371546,
ENSP00000383108,
ENSP00000496532,
ENSP00000493489,
ENSP00000440210,
ENSP00000383101,
ENSP00000494406,
ENSP00000495917,
ENSP00000498382
RefSeq:
NP_001351247.1,
XP_011528865.1,
NP_001350783.1,
NP_001356831.1,
XP_016884603.1,
XP_016884602.1,
XP_016884604.1,
XP_011528870.1,
XP_011528867.1,
NP_001356832.1,
NP_001229825.1,
XP_011528864.1,
NP_001356830.1,
XP_011528863.1,
NP_001007189.1,
XP_024308073.1,
NP_001229826.1,
XP_011528859.1,
NP_001351249.1,
NP_001351248.1,
NP_055477.1,
NP_001129501.1,
NP_001350781.1,
XP_011528871.1
|
| Others |
UniRef100:
UniRef100_O75140
UniRef90:
UniRef90_O75140
UniRef50:
UniRef50_O75140
UniGene:
Hs.435022
CCDS:
CCDS56229.1,
CCDS87017.1,
CCDS43007.1,
CCDS74849.1,
CCDS46692.1,
CCDS43006.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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